5-LOX-IN-1

Modify Date: 2024-01-13 18:12:51

5-LOX-IN-1 Structure
5-LOX-IN-1 structure
Common Name 5-LOX-IN-1
CAS Number 55040-82-9 Molecular Weight 350.43
Density N/A Boiling Point N/A
Molecular Formula C20H18N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-LOX-IN-1


5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].

 Names

Name Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-

 5-LOX-IN-1 Biological Activity

Description 5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].
Related Catalog
Target

IC50: 2.3 μM (5-LOX)[1]

In Vitro 5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM[1].
References

[1]. Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50.

 Chemical & Physical Properties

Molecular Formula C20H18N2O2S
Molecular Weight 350.43
Storage condition -20°C