2,3,5-Tri-O-benzyl-D-ribonolactone

Modify Date: 2024-01-17 17:31:21

2,3,5-Tri-O-benzyl-D-ribonolactone Structure
2,3,5-Tri-O-benzyl-D-ribonolactone structure
Common Name 2,3,5-Tri-O-benzyl-D-ribonolactone
CAS Number 55094-52-5 Molecular Weight 418.48
Density 1.21±0.1 g/cm3 Boiling Point 576.8±50.0 °C
Molecular Formula C26H26O5 Melting Point 54-55 °C
MSDS N/A Flash Point N/A

 Use of 2,3,5-Tri-O-benzyl-D-ribonolactone


2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name (3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one
Synonym More Synonyms

 2,3,5-Tri-O-benzyl-D-ribonolactone Biological Activity

Description 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.21±0.1 g/cm3
Boiling Point 576.8±50.0 °C
Melting Point 54-55 °C
Molecular Formula C26H26O5
Molecular Weight 418.48
Exact Mass 418.17800
PSA 53.99000
LogP 4.29940

 Safety Information

Hazard Codes Xi

 Synonyms

(3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-one
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