Soyasaponin II
Modify Date: 2024-01-05 17:27:51
Soyasaponin II structure
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Common Name | Soyasaponin II | ||
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| CAS Number | 55319-36-3 | Molecular Weight | 913.09600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C47H76O17 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Soyasaponin IISoyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure[1][2]. |
| Name | soyasaponin II |
|---|---|
| Synonym | More Synonyms |
| Description | Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure[1][2]. |
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| Related Catalog | |
| Target |
HSV-1:54 μM (IC50) HIV-1:112 μM (IC50) influenza virus:88 μM (IC50) HCMV:104 μM (IC50) NLRP3 inflammasome |
| In Vitro | Soyasaponin II inhibits the replication of HSV-1 (IC50=54μM), HCMV (104μM), influenza virus (88μM), and HIV-1 (112 μM)[1]. |
| In Vivo | Soyasaponin II (5 mg/kg; p.o.; once a day for three consecutive days) ameliorates canonical NLRP3 inflammasome-associated innate immune response[2]. |
| References |
| Molecular Formula | C47H76O17 |
|---|---|
| Molecular Weight | 913.09600 |
| Exact Mass | 912.50800 |
| PSA | 274.75000 |
| LogP | 1.34370 |
| Hazard Codes | Xi |
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| MFCD04039836 |