[Nle13]-Motilin

Modify Date: 2024-01-16 11:51:17

[Nle13]-Motilin Structure
[Nle13]-Motilin structure
Common Name [Nle13]-Motilin
CAS Number 55524-56-6 Molecular Weight 2681.01
Density N/A Boiling Point N/A
Molecular Formula C121H190N34O35 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of [Nle13]-Motilin


[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist[1][2].

 Names

Name motilin, Nle(13)-

 [Nle13]-Motilin Biological Activity

Description [Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist[1][2].
Related Catalog
In Vitro [Nle13]-Motilin (0.1-30 nM, 15 min) increases the amplitude of electrically-evoked, neuronally-mediated contractions in the isolated gastric antrum[1]. [Nle13]-Motilin (0.3 μM, 10 min) induces a moderate increase in spontaneous contractility in the stomach[2].
References

[1]. Dass NB, et al. The rabbit motilin receptor: molecular characterisation and pharmacology. Br J Pharmacol. 2003 Nov;140(5):948-54.

[2]. Venkova K, et al. Effect of TZP-201, a novel motilin receptor antagonist, in the colon of the musk shrew (Suncus murinus). J Pharm Pharmacol. 2009 Mar;61(3):367-73.

 Chemical & Physical Properties

Molecular Formula C121H190N34O35
Molecular Weight 2681.01