Imidocarb dipropionate

Modify Date: 2024-01-02 21:08:37

Imidocarb dipropionate structure	Common Name	Imidocarb dipropionate
	CAS Number	55750-06-6	Molecular Weight	496.559
	Density	1.39g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₂N₆O₅	Melting Point	205ºC
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of Imidocarb dipropionate

Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL[1].

Name	1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea,propanoic acid
Synonym	More Synonyms

Description	Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 87 μg/mL (Parasite B. bovis)[1]
In Vivo	Imidocarb dipropionate is administered by subcutaneous or intramuscular injection to horses (3.4 mg/kg bw) and cattle (2.I mg/kg bw). In horses, up to 4 doses may be given at 72-hour intervals. A second dose may be given 2 weeks after the first[1]. Imidocarb dipropionate is also used in sheep (1. 2mg/kg bw) for the treatment of babesiosis and anaplasmosis[1]. The acute oral LD50 value of Imidocarb dipropionate is in the range of 646 to 723 mg/kg bw in mice[1]. The acute oral LD50 value of Imidocarb is in the range of 454 to 1251 mg/kg bw in rats[1].
References	[1]. Rodriguez RI, et al. In vitro responsiveness of Babesia bovis to Imidocarb dipropionate and the selection of a drug-adapted line. Vet Parasitol. 1996 Mar;62(1-2):35-41.

Density	1.39g/cm3
Melting Point	205ºC
Molecular Formula	C₂₅H₃₂N₆O₅
Molecular Weight	496.559
Exact Mass	496.243408
PSA	164.51000
LogP	2.66700

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
RIDADR	NONH for all modes of transport
WGK Germany	3

Comparison of glycopyrrolate and atropine in ameliorating the adverse effects of imidocarb dipropionate in horses.

Equine Vet. J. 45(5) , 625-9, (2013)

Imidocarb, an effective treatment for piroplasmosis, may cause colic and diarrhoea in horses. Atropine and glycopyrrolate are anticholinergics that could reduce the adverse effects of imidocarb. Howev...

Failure of combination therapy with imidocarb dipropionate and toltrazuril to clear Hepatozoon canis infection in dogs.

Parasitol. Res. 109(3) , 919-26, (2011)

Current treatments with imidocarb dipropionate for infected dogs with Hepatozoon canis do not always provide parasitological cure. The objective of this study is to determine whether concomitant use o...

Alterations in some blood coagulation parameters in naturally occurring cases of canine babesiosis.

Acta Vet. Hung. 57(2) , 295-304, (2009)

Changes in coagulation parameters were studied in dogs naturally infected with Babesia canis canis (n = 30), and haemostasis was evaluated and compared to values obtained from healthy dogs (n = 29). T...

MFCD00013161

Imizol

Imidocarb Dipropionate

Propanoic acid - 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea (2:1)

Propanoic acid, compd. with urea, N,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]- (2:1)

EINECS 259-791-8