3-(2,4-Dihydroxyphenyl)propionic acid

Modify Date: 2024-01-02 15:45:57

3-(2,4-Dihydroxyphenyl)propionic acid structure	Common Name	3-(2,4-Dihydroxyphenyl)propionic acid
	CAS Number	5631-68-5	Molecular Weight	182.173
	Density	1.4±0.1 g/cm3	Boiling Point	418.0±14.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₀O₄	Melting Point	158-162ºC
	MSDS	Chinese USA	Flash Point	220.8±16.6 °C

Use of 3-(2,4-Dihydroxyphenyl)propionic acid

3-(2,4-Dihydroxyphenyl)propanoic acid (DPPacid) is a potent and competitive tyrosinase inhibitor, inhibits L-Tyrosine and DL-DOPA with an IC50 and a Ki of 3.02 μM and 11.5 μM, respectively[1].

Name	3-(2,4-Dihydroxyphenyl)propanoic acid
Synonym	More Synonyms

Description	3-(2,4-Dihydroxyphenyl)propanoic acid (DPPacid) is a potent and competitive tyrosinase inhibitor, inhibits L-Tyrosine and DL-DOPA with an IC50 and a Ki of 3.02 μM and 11.5 μM, respectively[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase
Target	Ki: 3.02 μM (L-Tyrosine); 11.5 μM (DL-DOPA)[1]
References	[1]. Shimizu K, et al. Novel vitamin E derivative with 4-substituted resorcinol moiety has both antioxidant and tyrosinase inhibitory properties. Lipids. 2001 Dec;36(12):1321-6.

Density	1.4±0.1 g/cm3
Boiling Point	418.0±14.0 °C at 760 mmHg
Melting Point	158-162ºC
Molecular Formula	C₉H₁₀O₄
Molecular Weight	182.173
Flash Point	220.8±16.6 °C
Exact Mass	182.057907
PSA	77.76000
LogP	0.38
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.620

3-(2,4-Dihydroxyphenyl)propionic acid MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2918290000

Precursor 10
CAS#:542-76-7 3-chloropropion... CAS#:108-46-3 Resorcine CAS#:2141-62-0 3-Ethoxypropane... CAS#:107-13-1 Acrylonitrile
CAS#:93-35-6 7-Hydroxycoumarine CAS#:5631-67-4 7-Hydroxy-2-chr... CAS#:412017-21-1 7-acetoxy-chrom... CAS#:7732-18-5 Water
CAS#:7647-01-0 Hydrochloric acid CAS#:60-29-7 Diethyl ether
DownStream 4
CAS#:108-46-3 Resorcine CAS#:17422-90-1 Methyl 3-(2,4-d... CAS#:22174-29-4 3-(2,4-Dimethox... CAS#:5631-67-4 7-Hydroxy-2-chr...

HS Code	2918290000
Summary	HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

The use of enzyme-coupled magnetic nanoparticles for studying the spectra of unusual substrates of mushroom tyrosinase by direct surface-assisted laser desorption/ionisation and high-resolution electrospray ionisation quadrupole-quadrupole-time-of-flight mass spectrometry.

Rapid Commun. Mass Spectrom. 28(18) , 1957-63, (2014)

Tyrosinase-coupled magnetic particles (EMPs) were used to demonstrate that resorcinol-containing tyrosinase inhibitors are oxidised by tyrosinase only in the presence of the enzyme's classic substrate...

The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage.

Biochem. J. 330 ( Pt 3) , 1059-67, (1998)

A major product of hydroxy-radical addition to tyrosine is 3, 4-dihydroxyphenylalanine (DOPA) which has reducing properties. Protein-bound DOPA (PB-DOPA) has been shown to be a major component of the ...

Phenoloxidase and QX disease resistance in Sydney rock oysters (Saccostrea glomerata).

Dev. Comp. Immunol. 28(6) , 565-9, (2004)

QX is a fatal disease in Sydney rock oysters (Saccostrea glomerata) that results from infection by the protistan parasite, Marteilia sydneyi. Since 1997, the New South Wales Fisheries Service has bred...

3-(2,4-Dihydroxyphenyl)propanoic acid

Benzenepropanoic acid, 2,4-dihydroxy-

MFCD00143017