3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine

Modify Date: 2024-01-15 21:10:43

3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine Structure
3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine structure
Common Name 3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine
CAS Number 565226-18-8 Molecular Weight 456.16
Density N/A Boiling Point N/A
Molecular Formula C13H14FIN2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine


3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-iodo-3',5'-diacetyl-2'-fluoro-2'-deoxyuridine
Synonym More Synonyms

  Biological Activity

Description 3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C13H14FIN2O7
Molecular Weight 456.16
Exact Mass 455.98300
PSA 116.69000

 Synonyms

3'',5''-diacetyl-5-iodo-2''-fluoro-2''-deoxyuridine
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