Formestane
Modify Date: 2026-07-01 21:13:48
Formestane structure
|
Common Name | Formestane | ||
|---|---|---|---|---|
| CAS Number | 566-48-3 | Molecular Weight | 302.408 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 475.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H26O3 | Melting Point | 199-202°C | |
| MSDS | Chinese USA | Flash Point | 255.4±25.2 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
| Name | formestane |
|---|---|
| Synonym | More Synonyms |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 475.4±45.0 °C at 760 mmHg |
| Melting Point | 199-202°C |
| Molecular Formula | C19H26O3 |
| Molecular Weight | 302.408 |
| Flash Point | 255.4±25.2 °C |
| Exact Mass | 302.188202 |
| PSA | 54.37000 |
| LogP | 2.66 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.570 |
| InChIKey | OSVMTWJCGUFAOD-KZQROQTASA-N |
| SMILES | CC12CCC3C(CCC4=C(O)C(=O)CCC43C)C1CCC2=O |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360 |
| Precautionary Statements | P201-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic |
| Risk Phrases | R60 |
| Safety Phrases | S53-S36/37/39-S45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | BV8152500 |
|
Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.
PLoS ONE 7 , e36069, (2012) The tg(cyp19a1b-GFP) transgenic zebrafish expresses GFP (green fluorescent protein) under the control of the cyp19a1b gene, encoding brain aromatase. This gene has two major characteristics: (i) it is... |
|
|
Combined inhibitory effect of formestane and herceptin on a subpopulation of CD44+/CD24low breast cancer cells.
Cancer Sci. 101 , 1661-9, (2010) In breast cancer, stromal cells surrounding cancer epithelial cells can influence phenotype by producing paracrine factors. Among many mediators of epithelial-stromal interactions, aromatase activity ... |
|
|
The effects of aromatase inhibitors and selective estrogen receptor modulators on eye development in the zebrafish (Danio rerio).
Curr. Eye Res. 32(10) , 819-27, (2007) It has been shown that the steroid hormone estrogen plays an important role in the development of the central nervous system. The purpose of these studies was to determine the effect of estrogen on ze... |
|
Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
|
|
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
|
|
Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
|
|
Name: Inhibition of human aromatase extracted from placental microsomes using [1beta-3H]and...
Source: ChEMBL
Target: Aromatase
External Id: CHEMBL3755860
|
|
Name: Inhibition of cytochrome P450 19A1 aromatase from human placental microsomes
Source: ChEMBL
Target: Aromatase
External Id: CHEMBL645585
|
|
Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
|
|
Name: Inhibition of aromatase in denucleated ovarian fraction extracted from PMSG pretreate...
Source: ChEMBL
Target: Aromatase
External Id: CHEMBL3757109
|
Total 635, Current Page 1 of 64
1
2
3
4
5
| 4-Hydroxyandrost-4-ene-3,17-dione |
| 4-Hydroxy-4-androstene-3,17-dione |
| Formestane |
| B,Aromatase inhibitor |
| Lentaron |
| 4-androsten-4-ol-3,17-dione |
| 4-Hydroxyandrostenedione |
| 4-OH-A |
| MFCD00057814 |
| (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione |