16α-Hydroxyestrone

Modify Date: 2025-09-05 12:45:27

16α-Hydroxyestrone Structure
16α-Hydroxyestrone structure
Common Name 16α-Hydroxyestrone
CAS Number 566-76-7 Molecular Weight 286.366
Density 1.3±0.1 g/cm3 Boiling Point 493.2±45.0 °C at 760 mmHg
Molecular Formula C18H22O3 Melting Point 209-211ºC
MSDS N/A Flash Point 266.2±25.2 °C

 Use of 16α-Hydroxyestrone


16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease[1].

 Names

Name 16α-hydroxyestrone
Synonym More Synonyms

 16α-Hydroxyestrone Biological Activity

Description 16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease[1].
Related Catalog
In Vitro Increasing levels of active estrogen metabolites, 16α-Hydroxyestrone and E3, are associated with increasing bone mineral densit[1].
References

[1]. Napoli N, et al , Armamento-Villareal R. Estrogen metabolism modulates bone density in men. Calcif Tissue Int. 2007;80(4):227-232.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 493.2±45.0 °C at 760 mmHg
Melting Point 209-211ºC
Molecular Formula C18H22O3
Molecular Weight 286.366
Flash Point 266.2±25.2 °C
Exact Mass 286.156891
PSA 57.53000
LogP 2.32
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.612

 Safety Information

Hazard Codes Xn
Risk Phrases R40
Safety Phrases S22-S36

 Synonyms

3,16-Dihydroxyestra-1(10),2,4-trien-17-one
Estra-1,3,5(10)-triene-3,16a-diol-17-one
Estra-1(10),2,4-trien-17-one, 3,16-dihydroxy-, (16α)-
Estra-1,3,5(10)-trien-17-one, 3,16α-dihydroxy-
(16α)-3,16-Dihydroxyestra-1(10),2,4-trien-17-one
1,3,5[10]-ESTRATRIENE-3,16ALPHA-DIOL-17-ONE
3,16-Dihydroxyestra-1,3,5(10)-trien-17-one
Estra-1(10),2,4-trien-17-one, 3,16-dihydroxy-
3,16a-dihydroxy-Estra-1,3,5(10)-trien-17-one
estra-1,3,5(10)-trien-17-one, 3,16-dihydroxy-, (16α)-
16ALPHA-HYDROXYESTERONE
16α-Hydroxy Estrone
16alpha-hydroxyestrone
16Alpha-Hydroxy Estrone
3,16-dihydroxy-Estra-1,3,5(10)-trien-17-one
3,16α-Dihydroxyestra-1,3,5(10)-trien-17-one
Estra-1,3,5(10)-trien-17-one, 3,16-dihydroxy-
16A-hydroxyestrone
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