![]() THDOC structure
|
Common Name | THDOC | ||
---|---|---|---|---|
CAS Number | 567-02-2 | Molecular Weight | 334.49300 | |
Density | 1.115g/cm3 | Boiling Point | 470.3ºC at 760mmHg | |
Molecular Formula | C21H34O3 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 252.3ºC |
Use of THDOC3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro. |
Name | 2-hydroxy-1-[(8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone |
---|---|
Synonym | More Synonyms |
Description | 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro. |
---|---|
Related Catalog |
Density | 1.115g/cm3 |
---|---|
Boiling Point | 470.3ºC at 760mmHg |
Molecular Formula | C21H34O3 |
Molecular Weight | 334.49300 |
Flash Point | 252.3ºC |
Exact Mass | 334.25100 |
PSA | 57.53000 |
LogP | 3.56760 |
Index of Refraction | 1.54 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
RIDADR | NONH for all modes of transport |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc... |
|
A quantitiative LC-MS/MS method for the measurement of arachidonic acid, prostanoids, endocannabinoids, N-acylethanolamines and steroids in human plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 976-977 , 6-18, (2015) Free arachidonic acid is functionally interlinked with different lipid signaling networks including those involving prostanoid pathways, the endocannabinoid system, N-acylethanolamines, as well as ste... |
|
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened... |
[3H]-Allotetrahydrodeoxycorticosterone |
21-HYDROXYALLOPREGNANOLONE |
TDOC |
ALLOTETRADEOXYCORTICOSTERONE |
ALLOTETRAHYDRO DOC |
ALLOTETRAHYDRO SUBSTANCE 'Q' |
ALLOTETRAHYDRODEOXYCORTICOSTERONE |
ALLOTETRAHYDROCORTEXONE |
ALLO TH DOC |
5A-pregnane-3A,21-diol-20-one |