THDOC

Modify Date: 2025-08-27 12:42:35

THDOC Structure
THDOC structure
Common Name THDOC
CAS Number 567-02-2 Molecular Weight 334.49300
Density 1.115g/cm3 Boiling Point 470.3ºC at 760mmHg
Molecular Formula C21H34O3 Melting Point N/A
MSDS Chinese USA Flash Point 252.3ºC

 Use of THDOC


3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.

 Names

Name 2-hydroxy-1-[(8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Synonym More Synonyms

 THDOC Biological Activity

Description 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.
Related Catalog

 Chemical & Physical Properties

Density 1.115g/cm3
Boiling Point 470.3ºC at 760mmHg
Molecular Formula C21H34O3
Molecular Weight 334.49300
Flash Point 252.3ºC
Exact Mass 334.25100
PSA 57.53000
LogP 3.56760
Index of Refraction 1.54
InChIKey CYKYBWRSLLXBOW-GDYGHMJCSA-N
SMILES CC12CCC(O)CC1CCC1C2CCC2(C)C(C(=O)CO)CCC12

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles32

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Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

 Synonyms

[3H]-Allotetrahydrodeoxycorticosterone
21-HYDROXYALLOPREGNANOLONE
TDOC
ALLOTETRADEOXYCORTICOSTERONE
ALLOTETRAHYDRO DOC
ALLOTETRAHYDRO SUBSTANCE 'Q'
ALLOTETRAHYDRODEOXYCORTICOSTERONE
ALLOTETRAHYDROCORTEXONE
ALLO TH DOC
5A-pregnane-3A,21-diol-20-one
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