567-02-2

567-02-2 structure

Name: THDOC
Chemical Name: 2-hydroxy-1-[(8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
CAS Number: 567-02-2
Molecular Formula: C₂₁H₃₄O₃
Molecular Weight: 334.49300
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2018-12-27 17:16:48
Modify Date: 2025-08-27 12:42:35
3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.

Name	2-hydroxy-1-[(8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Synonyms	[3H]-Allotetrahydrodeoxycorticosterone 21-HYDROXYALLOPREGNANOLONE TDOC ALLOTETRADEOXYCORTICOSTERONE ALLOTETRAHYDRO DOC ALLOTETRAHYDRO SUBSTANCE 'Q' ALLOTETRAHYDRODEOXYCORTICOSTERONE ALLOTETRAHYDROCORTEXONE ALLO TH DOC 5A-pregnane-3A,21-diol-20-one

Description	3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

Precursor 4
516-54-1 516-55-2 566-65-4 225518-89-8
DownStream 0