2-Chlorophenoxazine

Modify Date: 2024-12-02 07:24:29

2-Chlorophenoxazine Structure
2-Chlorophenoxazine structure
 Common Name 2-Chlorophenoxazine
CAS Number 56821-03-5 Molecular Weight 217.65
Density N/A Boiling Point N/A
Molecular Formula C12H8ClNO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Chlorophenoxazine


2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis.2-Chlorophenoxazine can be used for cancer diseases research[1].

 Names

Name 2-chloro-10H-phenoxazine
Synonym More Synonyms

 2-Chlorophenoxazine Biological Activity

Description 2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis.2-Chlorophenoxazine can be used for cancer diseases research[1].
Related Catalog
References

[1]. Thimmaiah KN, et al. Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35  

 Chemical & Physical Properties

Molecular Formula C12H8ClNO
Molecular Weight 217.65
Exact Mass 217.02900
PSA 21.26000
LogP 4.32730

 Synthetic Route

2-chloro-10H-phenoxazine-10-carboxaldehyde structure

2-chloro-10H-ph...

CAS#:60344-80-1

~75%

2-Chlorophenoxazine Structure

2-Chlorophenoxazine

CAS#:56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259
2-Bromophenol structure

2-Bromophenol

CAS#:95-56-7

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2-Chlorophenoxazine Structure

2-Chlorophenoxazine

CAS#:56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259
1-(2-bromophenoxy)-4-chloro-2-nitro-benzene structure

1-(2-bromopheno...

CAS#:105837-78-3

~%

2-Chlorophenoxazine Structure

2-Chlorophenoxazine

CAS#:56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259
2-amino-4-chloro-2'-bromodiphenylether structure

2-amino-4-chlor...

CAS#:105790-01-0

~%

2-Chlorophenoxazine Structure

2-Chlorophenoxazine

CAS#:56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259
1,4-Dichloro-2-nitrobenzene structure

1,4-Dichloro-2-...

CAS#:89-61-2

~%

2-Chlorophenoxazine Structure

2-Chlorophenoxazine

CAS#:56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259
N-[2-(2-bromophenoxy)-5-chlorophenyl]formamide structure

N-[2-(2-bromoph...

CAS#:320785-96-4

~%

2-Chlorophenoxazine Structure

2-Chlorophenoxazine

CAS#:56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259
9-chloro-[1,2,3]triazolo[4,5,1-kl]phenoxazine structure

9-chloro-[1,2,3...

CAS#:108953-08-8

~%

2-Chlorophenoxazine Structure

2-Chlorophenoxazine

CAS#:56821-03-5

Literature: Cieslak,J. et al. Roczniki Chemii, 1960 , vol. 34, p. 103 - 110

 Synonyms

2-chlorophenoxazine
10H-Phenoxazine,2-chloro
2-chlorphenoxazine
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