Butoxamine hydrochloride

Modify Date: 2024-01-05 12:49:04

Butoxamine hydrochloride Structure
Butoxamine hydrochloride structure
Common Name Butoxamine hydrochloride
CAS Number 5696-15-1 Molecular Weight 303.82500
Density N/A Boiling Point 391ºC at 760 mmHg
Molecular Formula C15H26ClNO3 Melting Point N/A
MSDS Chinese USA Flash Point 190.3ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Butoxamine hydrochloride


Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats[1].

 Names

Name 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol,hydrochloride
Synonym More Synonyms

 Butoxamine hydrochloride Biological Activity

Description Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats[1].
Related Catalog
Target

Beta-2 adrenergic receptor

In Vivo Butaxamine hydrochloride(25 μg/kg/min、50 μg/kg/min、100 μg/kg/min,15 分钟;静脉注射)提高了乙醇麻醉、水利尿大鼠的尿量水平[1]。
References

[1]. Shibouta Y, et al. Antidiuresis induced by beta1- and beta2-adrenergic agonists in ethanol-anesthetized rats. Eur J Pharmacol. 1978 Jan 15;47(2):149-57.  

 Chemical & Physical Properties

Boiling Point 391ºC at 760 mmHg
Molecular Formula C15H26ClNO3
Molecular Weight 303.82500
Flash Point 190.3ºC
Exact Mass 303.16000
PSA 50.72000
LogP 3.70670

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22-36
Safety Phrases 26
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles25

More Articles
Restoration of neutrophil immunocompetence after cardiopulmonary bypass by beta-adrenergic blockers.

Surgery 147(4) , 562-74, (2010)

To evaluate the possible protective effect of sympatholytic medications with respect to neutrophil function, we evaluated the influence of a nonselective beta-blocker medication on the interaction of ...

Does selective beta-1 blockade provide bone marrow protection after trauma/hemorrhagic shock?

Surgery 152(3) , 322-30, (2012)

Previously, nonselective beta-blockade (BB) with propranolol demonstrated protection of the bone marrow (BM) after trauma and hemorrhagic shock (HS). Because selective beta-1 blockers are used commonl...

Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal.

Psychoneuroendocrinology 33(10) , 1411-8, (2008)

Hypoglycemia is associated with a variety of adverse behaviors including fatigue, confusion and social withdrawal. While these clinical symptoms are well characterized, the mechanism of their cause is...

 Synonyms

N-tert.-Butyl-pseudomethoxaminhydrochlorid
BUTOXAMINE HYDROCHLORIDE
Butoxamine hydrochloride (USAN)
BW 64-9
Butoxamine HCl
N-tert-Butylmethoxamine hydrochloride
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