Z-Leu-Tyr-chloromethylketone

Modify Date: 2024-04-08 16:30:16

Z-Leu-Tyr-chloromethylketone Structure
Z-Leu-Tyr-chloromethylketone structure
Common Name Z-Leu-Tyr-chloromethylketone
CAS Number 56979-35-2 Molecular Weight 460.95000
Density 1.231g/cm3 Boiling Point 693.5ºC at 760mmHg
Molecular Formula C24H29ClN2O5 Melting Point N/A
MSDS N/A Flash Point 373.2ºC

 Use of Z-Leu-Tyr-chloromethylketone


Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor[1].

 Names

Name N2-[(Benzyloxy)carbonyl]-N-[(2S)-4-chloro-1-(4-hydroxyphenyl)-3-oxo-2-butanyl]-L-leucinamide

 Z-Leu-Tyr-chloromethylketone Biological Activity

Description Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor[1].
Related Catalog
Target

IC50: calpain[1]

References

[1]. L Ditzel, et al. Structural investigation of proteasome inhibition. Biol Chem. 1997 Mar-Apr;378(3-4):239-47.

 Chemical & Physical Properties

Density 1.231g/cm3
Boiling Point 693.5ºC at 760mmHg
Molecular Formula C24H29ClN2O5
Molecular Weight 460.95000
Flash Point 373.2ºC
Exact Mass 460.17600
PSA 111.71000
LogP 4.61320
Index of Refraction 1.566