11-Maleimidoundecanoic acid

Modify Date: 2025-08-20 21:18:52

11-Maleimidoundecanoic acid structure	Common Name	11-Maleimidoundecanoic acid
	CAS Number	57079-01-3	Molecular Weight	281.347
	Density	1.1±0.1 g/cm3	Boiling Point	452.8±18.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₃NO₄	Melting Point	89-90ºC
	MSDS	Chinese USA	Flash Point	227.6±21.2 °C
	Symbol	GHS07	Signal Word	Warning

Use of 11-Maleimidoundecanoic acid

11-Maleimidoundecanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	11-(2,5-dioxopyrrol-1-yl)undecanoic acid
Synonym	More Synonyms

Description	11-Maleimidoundecanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.1±0.1 g/cm3
Boiling Point	452.8±18.0 °C at 760 mmHg
Melting Point	89-90ºC
Molecular Formula	C₁₅H₂₃NO₄
Molecular Weight	281.347
Flash Point	227.6±21.2 °C
Exact Mass	281.162720
PSA	74.68000
LogP	3.36
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.515
Storage condition	-20°C

11-Maleimidoundecanoic acid MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
RIDADR	NONH for all modes of transport
HS Code	2925190090

Precursor 2
CAS#:57079-16-0 N-(10-Carboxyde... CAS#:2432-99-7 11-Aminoundecan...
DownStream 0

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synthesis of Heterotelechelic Polymers for Conjugation of Two Different Proteins.

Macromolecules 42 , 2360, (2009)

In this report we describe a straightforward approach to synthesize polymers with end-groups that bind site-specifically to two different proteins. Telechelic biotin, maleimide poly(N-isopropylacrylam...

Safak, M.; Alemdaroglu, F. E.; Li, Y.; Ergen, E.; Hernnann, A.

Adv. Mater. 19 , 1499, (2007)

11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid

11-maleimido-undecanoic acid

1H-Pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo-

UNII-LG78EY7HVB

maleimidoundecanoic acid