Fraxetin

Modify Date: 2024-01-02 16:25:24

Fraxetin structure	Common Name	Fraxetin
	CAS Number	574-84-5	Molecular Weight	208.167
	Density	1.5±0.1 g/cm3	Boiling Point	472.0±45.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₈O₅	Melting Point	230-232°C
	MSDS	Chinese USA	Flash Point	196.0±22.2 °C
	Symbol	GHS07	Signal Word	Warning

Use of Fraxetin

Fraxetin is isolated from Cortex Fraxini. Fraxetin has antitumor, anti-oxidation effects and anti-inflammory effects. Fraxetin induces apoptosis[1].

Name	7,8-dihydroxy-6-methoxychromen-2-one
Synonym	More Synonyms

Description	Fraxetin is isolated from Cortex Fraxini. Fraxetin has antitumor, anti-oxidation effects and anti-inflammory effects. Fraxetin induces apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis
References	[1]. Chen X, et al. The therapeutic effect of fraxetin on ethanol-induced hepatic fibrosis by enhancing ethanol metabolism, inhibiting oxidative stress and modulating inflammatory mediators in rats. Int Immunopharmacol. 2018 Mar;56:98-104. [2]. Liu G, et al. Effect of fraxetin on proliferation and apoptosis in breast cancer cells. Oncol Lett. 2017 Dec;14(6):7374-7378.

Description

Fraxetin is isolated from Cortex Fraxini. Fraxetin has antitumor, anti-oxidation effects and anti-inflammory effects. Fraxetin induces apoptosis[1].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

References

[1]. Chen X, et al. The therapeutic effect of fraxetin on ethanol-induced hepatic fibrosis by enhancing ethanol metabolism, inhibiting oxidative stress and modulating inflammatory mediators in rats. Int Immunopharmacol. 2018 Mar;56:98-104.

[2]. Liu G, et al. Effect of fraxetin on proliferation and apoptosis in breast cancer cells. Oncol Lett. 2017 Dec;14(6):7374-7378.

Density	1.5±0.1 g/cm3
Boiling Point	472.0±45.0 °C at 760 mmHg
Melting Point	230-232°C
Molecular Formula	C₁₀H₈O₅
Molecular Weight	208.167
Flash Point	196.0±22.2 °C
Exact Mass	208.037170
PSA	79.90000
LogP	0.59
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.648
Storage condition	2~8°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R20/21/22;R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
HS Code	2932209090

Precursor 8
CAS#:73815-12-0 fraxetin diacetate CAS#:4055-69-0 2,3-dihydroxy-4... CAS#:71765-80-5 6-Methoxy-7-(3-... CAS#:77369-04-1 obtusicin
CAS#:667876-16-6 2,3-di[(isoprop... CAS#:2103-57-3 2,3,4-Trimethox... CAS#:24778-11-8 7-β-D-glucopyra... CAS#:89019-07-8 8-Acetyl-7-meth...
DownStream 6
CAS#:486-21-5 Isofraxidin CAS#:525-21-3 Fraxidin CAS#:28843-40-5 7,8-METHYLENEDI... CAS#:6035-49-0 6,7,8-Trimethox...
CAS#:114371-80-1 6,7,8-trihydrox... CAS#:84575-10-0 Cleomiscosin C

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

[Studies on chemical constituents from stem barks of Fraxinus paxiana].

Zhongguo Zhong Yao Za Zhi 33(16) , 1990-3, (2008)

To investigate the chemical constituents of Fraxinus paxiana.The chemical constituents were isolated and purified by chromatographic techniques and the structures of the compounds were identified with...

Antihyperglycemic effect of fraxetin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats.

Biochimie 95(10) , 1848-54, (2013)

Epidemiological studies have demonstrated that the diabetes mellitus is a serious health burden for both governments and healthcare providers. The present study was hypothesized to evaluate the antihy...

[Coumarins from branch of Fraxinus sieboldiana and their antioxidative activity].

Zhongguo Zhong Yao Za Zhi 33(14) , 1708-10, (2008)

To investigate the chemical constituents from the branch of Fraxinus sieboldiana, and evaluate their antioxidative activity.The chemical constituents were isolated and purified by chromatographic tech...

Coumarin, 7,8-dihydroxy-6-methoxy-

EINECS 209-376-2

6-methoxy-7,8-dihydroxycoumarin

7,8-Dihydroxy-6-methoxy-2H-chromen-2-one

2H-1-Benzopyran-2-one,7,8-dihydroxy-6-methoxy

7,8-Dihydroxy-6-methoxycoumarin

2H-1-Benzopyran-2-one, 7,8-dihydroxy-6-methoxy-

7,8-dihydroxy-6-methoxy-benzopyran-2-one

7,8-Dihydroxy-6-methoxy-2H-1-benzopyran-2-one

Fraxetin

MFCD00006873

BioBioPha
China
Product Name: Fraxetin
Price: ￥Inquiry/50mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Fraxetin
Price: ￥498.0/20mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Fraxetin
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fraxetin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: ￥429/250mg

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Fraxetin

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