4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid
4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid structure
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Common Name | 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid | ||
|---|---|---|---|---|
| CAS Number | 574-92-5 | Molecular Weight | 257.16500 | |
| Density | 1.55 g/cm3 | Boiling Point | 354.7ºC at 760 mmHg | |
| Molecular Formula | C11H6F3NO3 | Melting Point | 259-260 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 168.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.55 g/cm3 |
|---|---|
| Boiling Point | 354.7ºC at 760 mmHg |
| Melting Point | 259-260 °C (dec.)(lit.) |
| Molecular Formula | C11H6F3NO3 |
| Molecular Weight | 257.16500 |
| Flash Point | 168.3ºC |
| Exact Mass | 257.03000 |
| PSA | 70.42000 |
| LogP | 2.65740 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | VB2188000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~99%
4-Hydroxy-7-(tr... CAS#:574-92-5 |
| Literature: Garudachari; Isloor, Arun M.; Satyanarayana; Fun, Hoong-Kun; Pavithra; Kulal, Ananda European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 422 - 432 |
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4-Hydroxy-7-(tr... CAS#:574-92-5 |
| Literature: Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926 |
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4-Hydroxy-7-(tr... CAS#:574-92-5 |
| Literature: Journal of the American Chemical Society, , vol. 69, p. 371,373 |
![Propanedioic acid,2-[[[3-(trifluoromethyl)phenyl]amino]methylene]-, 1,3-diethyl ester structure](https://image.chemsrc.com/caspic/482/370-35-4.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
|---|---|
| DownStream 3 | |
CAS#:346-55-4
CAS#:322-97-4![N,N-diethyl-N-[7-(trifluoromethyl)quinolin-4-yl]pentane-1,4-diamine structure](https://image.chemsrc.com/caspic/030/442-85-3.png)
CAS#:442-85-3This table lists relevant public references with title, journal and publication metadata for this compound.
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Synthesis and testing of new antileukemic Schiff bases of N-hydroxy-N'-aminoguanidine against CCRF-CEM/0 human leukemia cells in vitro and synergism studies with cytarabine (Ara-C).
Pharm. Res. 10(4) , 515-20, (1993) A series of eight new N-hydroxy-N'-aminoguanidine (HAG) Schiff bases [ArCH = NNHC(= NH)NHOH.tosylate] was synthesized as potential antitumor agents through the inhibition of the enzyme ribonucleotide ... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00006771 |
| 4-hydroxy-7-trifluoromethyl-3-quinoline-carboxylic acid |
| EINECS 209-377-8 |
| 4-Hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid,HPLC |
| 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ACID |
| 4-hydroxy-7-(trifluoromethyl)-3-quinolinecarboxylicaci |
| 4-Hydroxy-7-trifluormethyl-chinolin-3-carbonsaeure |
| 3-Carboxy-4-hydroxy-7-trifluoromethylquinoline. |
| 7-trifluoromethyl-4-hydroxyquinoline-3-carboxylic acid |
| BUTTPARK 219-48 |
| 4-HYDROXY-7-TRIFLUOROMETHYL-3-QUINOLINE-CARBOXYLIC ACID,TECH. |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: Related upstream materials(CAS) of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid: 391-02-6;370-35-4;98-16-8. |
| Q: What is the melting point of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: Melting point of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is 259-260 °C (dec.)(lit.). |
| Q: What is the boiling point of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: Boiling point of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is 354.7ºC at 760 mmHg. |
| Q: What is the molecular weight of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: Molecular weight of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is 257.16500. |
| Q: What is the LogP of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: LogP of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is 2.65740. |
| Q: What is the CAS number of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: CAS number of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is 574-92-5. |
| Q: What is the molecular formula of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: Molecular formula of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is C11H6F3NO3. |
| Q: What are the downstream products of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: Related downstream products(CAS) of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid: 346-55-4;322-97-4;442-85-3. |
| Q: What is the polar surface area (PSA) of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: Polar surface area (PSA) of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is 70.42000. |
| Q: What is the English name of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid? |
| A: The English name of 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid is 4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |