Fexarine

Modify Date: 2024-01-02 12:31:05

Fexarine Structure
Fexarine structure
Common Name Fexarine
CAS Number 574013-67-5 Molecular Weight 497.58
Density 1.2±0.1 g/cm3 Boiling Point 681.2±55.0 °C at 760 mmHg
Molecular Formula C31H31NO5 Melting Point N/A
MSDS N/A Flash Point 365.8±31.5 °C

 Use of Fexarine


Fexarine is a potent, non-steroidal and selective agonist of farnesoid X receptor (EC50: 38 nM). Fexarine can be used for the research of diseases linked to cholesterol, bile acids[1].

 Names

Name (E)-methyl 3-(3-(N-(4-(benzo[d][1,3]dioxol-5-yl)benzyl)cyclohexanecarboxamido)phenyl)acrylate
Synonym More Synonyms

 Fexarine Biological Activity

Description Fexarine is a potent, non-steroidal and selective agonist of farnesoid X receptor (EC50: 38 nM). Fexarine can be used for the research of diseases linked to cholesterol, bile acids[1].
Related Catalog
In Vitro Fexarine (1 μM) 诱导 HT29-FXRFL 细胞中 IBABP mRNA 的表达[1]。
References

[1]. Michael R. Downes, et al. Non-steroidal farnesoid X receptor modulators and methods for the use thereof.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 681.2±55.0 °C at 760 mmHg
Molecular Formula C31H31NO5
Molecular Weight 497.58
Flash Point 365.8±31.5 °C
Exact Mass 497.220215
LogP 6.34
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.634

 Synonyms

2-Propenoic acid, 3-[3-[[[4-(1,3-benzodioxol-5-yl)phenyl]methyl](cyclohexylcarbonyl)amino]phenyl]-, methyl ester, (2E)-
MFCD29035146
methyl (2E)-3-(3-{[4-(1,3-benzodioxol-5-yl)benzyl](cyclohexylcarbonyl)amino}phenyl)prop-2-enoate
Methyl (2E)-3-(3-{[4-(1,3-benzodioxol-5-yl)benzyl](cyclohexylcarbonyl)amino}phenyl)acrylate
Fexarine
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