Hydrocortisone Valerate

Modify Date: 2024-01-06 18:11:47

Hydrocortisone Valerate Structure
Hydrocortisone Valerate structure
Common Name Hydrocortisone Valerate
CAS Number 57524-89-7 Molecular Weight 446.57600
Density 1.21g/cm3 Boiling Point 595.1ºC at 760mmHg
Molecular Formula C26H38O6 Melting Point 217-220 °C
MSDS Chinese USA Flash Point 195ºC
Symbol GHS08
GHS08
Signal Word Warning

 Use of Hydrocortisone Valerate


Hydrocortisone 17-valerate (Cortisol 17-valerate) is a thiazolidine compound[1].

 Names

Name cortisol 17-valerate
Synonym More Synonyms

 Hydrocortisone Valerate Biological Activity

Description Hydrocortisone 17-valerate (Cortisol 17-valerate) is a thiazolidine compound[1].
Related Catalog
References

[1]. Bodor N, et al. Soft drugs 4. 3-Spirothiazolidines of hydrocortisone and its derivatives[J]. International Journal of Pharmaceutics, 1982, 10(4): 307-321.

 Chemical & Physical Properties

Density 1.21g/cm3
Boiling Point 595.1ºC at 760mmHg
Melting Point 217-220 °C
Molecular Formula C26H38O6
Molecular Weight 446.57600
Flash Point 195ºC
Exact Mass 446.26700
PSA 100.90000
LogP 3.52270
Index of Refraction 1.56

 Safety Information

Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H351
Precautionary Statements P281
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn
Risk Phrases 40
Safety Phrases 22-36
RIDADR NONH for all modes of transport
WGK Germany 3

 Precursor & DownStream

Precursor  0

DownStream  1

 Articles14

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Compounding compatibility studies of four corticosteroid cream products and four commonly added chemicals are presented. Physical alteration, chemical stability, micropreservative challenge status, an...

Addition of a topically applied corticosteroid to a modified Goeckerman regimen for treatment of psoriasis: effect on duration of remission.

J. Am. Acad. Dermatol. 13(5 Pt 1) , 784-91, (1985)

A double-blind parallel group study was undertaken to assess the effect of adding a topically applied corticosteroid cream to a modified Goeckerman regimen to treat patients with psoriasis. Nineteen p...

Temporal infiltration of leukocyte subsets into mouse skin inflamed with phorbol ester.

Agents Actions 37(3-4) , 260-7, (1992)

We have previously shown that multiple topical applications, over 11 days, of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) induces a persistent inflammatory reaction characterized by e...

 Synonyms

CORTISOL 17-VALERATE
Flexicort
Westcort
HYDROCORTISONEVALERATE,USP
Hydrocortisone Valerate (200 mg)
cortisol valerate
hydrocortisone valerat
hydrocortisone-17-valerate
HYDROCORTISONE VALERATE