1-(Naphthalen-1-yl)piperazine

Modify Date: 2024-01-08 11:00:54

1-(Naphthalen-1-yl)piperazine Structure
1-(Naphthalen-1-yl)piperazine structure
Common Name 1-(Naphthalen-1-yl)piperazine
CAS Number 57536-86-4 Molecular Weight 248.75100
Density 1.106 g/cm3 Boiling Point 391.9ºC at 760 mmHg
Molecular Formula C14H17ClN2 Melting Point 280°C (dec.)
MSDS USA Flash Point 188.9ºC

 Names

Name 1-(1-naphthyl)piperazine hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.106 g/cm3
Boiling Point 391.9ºC at 760 mmHg
Melting Point 280°C (dec.)
Molecular Formula C14H17ClN2
Molecular Weight 248.75100
Flash Point 188.9ºC
Exact Mass 248.10800
PSA 15.27000
LogP 3.44520
Index of Refraction 1.622
Water Solubility H2O: soluble

 Safety Information

Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S26-S36/37/39
WGK Germany 3

 Synthetic Route

~%

1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Literature: BASF Aktiengesellschaft Patent: US6387912 B1, 2002 ;

~85%

1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Literature: Brenner, Eric; Schneider, Raphael; Fort, Yves Tetrahedron, 2002 , vol. 58, # 34 p. 6913 - 6924

~70%

1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Literature: Glennon, Richard A.; Slusher, R. M.; Lyon, Robert A.; Titeler, Milt; McKenney, J. D. Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2375 - 2380

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1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Detail
Literature: Nishiyama, Masakazu; Yamamoto, Toshihide; Koie, Yasuyuki Tetrahedron Letters, 1998 , vol. 39, # 7 p. 617 - 620

~43%

1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Literature: Konstantinova, Igor; Bukhryakov, Konstantin; Gezentsvey, Yuri; Krasavin, Mikhail Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 628 - 630

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1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Literature: Kerrigan, Frank; Martin, Claire; Thomas, Gerard H. Tetrahedron Letters, 1998 , vol. 39, # 15 p. 2219 - 2222

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1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Literature: Prelog; Blazek Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 211,218

~61%

1-(Naphthalen-1-yl)piperazine Structure

1-(Naphthalen-1...

CAS#:57536-86-4

Literature: Ghosh, Balaram; Antonio, Tamara; Zhen, Juan; Kharkar, Prashant; Reith, Maarten E. A.; Dutta, Aloke K. Journal of Medicinal Chemistry, 2010 , vol. 53, # 3 p. 1023 - 1037

 Synonyms

1-NAPHTHALENE-1-YL-PIPERAZINE HCL
naphthylpiperazine
1-NAPHTHALEN-1-YL-PIPERAZINE HYDROCHLORIDE
MFCD00055161
NPPI
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