5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one

Modify Date: 2025-11-27 20:09:20

5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one Structure
5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one structure
Common Name 5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one
CAS Number 577-26-4 Molecular Weight 302.23600
Density 1.763g/cm3 Boiling Point 714.6ºC at 760 mmHg
Molecular Formula C15H10O7 Melting Point N/A
MSDS N/A Flash Point 275.3ºC

 Names

Name 2-(4-hydroxyphenyl)-5,6,7,8-tetrahydroxy-4H-1-benzopyran-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.763g/cm3
Boiling Point 714.6ºC at 760 mmHg
Molecular Formula C15H10O7
Molecular Weight 302.23600
Flash Point 275.3ºC
Exact Mass 302.04300
PSA 131.36000
LogP 1.98800
Index of Refraction 1.804
InChIKey SPZXXUUDYMHBSG-UHFFFAOYSA-N
SMILES O=c1cc(-c2ccc(O)cc2)oc2c(O)c(O)c(O)c(O)c12

 Synthetic Route

~%

5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one Structure

5,6,7,8-tetrahy...

CAS#:577-26-4

Literature: Iinuma, Munekazu; Tanaka, Toshiyuki; Matsuura, Shin Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 3 p. 1006 - 1010

~%

5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one Structure

5,6,7,8-tetrahy...

CAS#:577-26-4

Literature: Murti et al. Proceedings - Indian Academy of Sciences, Section A, 1947 , # 26 p. 182,186

~%

5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one Structure

5,6,7,8-tetrahy...

CAS#:577-26-4

Literature: Murti et al. Proceedings - Indian Academy of Sciences, Section A, 1947 , # 26 p. 182,186

~%

5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one Structure

5,6,7,8-tetrahy...

CAS#:577-26-4

Literature: Murti et al. Proceedings - Indian Academy of Sciences, Section A, 1947 , # 26 p. 182,186

~%

5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one Structure

5,6,7,8-tetrahy...

CAS#:577-26-4

Literature: Murti et al. Proceedings - Indian Academy of Sciences, Section A, 1947 , # 26 p. 182,186

~%

5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one Structure

5,6,7,8-tetrahy...

CAS#:577-26-4

Literature: Murti et al. Proceedings - Indian Academy of Sciences, Section A, 1947 , # 26 p. 182,186

 Bioassay

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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Inhibition of diphenolase activity of mushroom tyrosinase at 0.055 mM
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL892345
Name: Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay
Source: 24386
Target: N/A
External Id: Sarm1 TIR NADase inhibitors
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 Synonyms

HMS2270F11
5,6,7,8-Tetrahydroxy-2-(4-hydroxy-phenyl)-chromen-4-on
Tris-nor-xanthomicrol
5,6,7,8,4'-Pentahydroxy-flavon
5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one
4',5,6,7,8-pentahydroxyflavone
Nortangeretin
5,6,7,8,4'-Pentahydroxyflavone
5,6,7,8-tetrahydroxy-2-(4-hydroxy-phenyl)-chromen-4-one
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