3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole

Modify Date: 2024-02-15 19:33:48

3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole Structure
3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole structure
Common Name 3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole
CAS Number 57845-06-4 Molecular Weight 367.27100
Density 1.26g/cm3 Boiling Point 497.1ºC at 760 mmHg
Molecular Formula C21H16Cl2N2 Melting Point N/A
MSDS N/A Flash Point 254.4ºC

 Names

Name 3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole

 Chemical & Physical Properties

Density 1.26g/cm3
Boiling Point 497.1ºC at 760 mmHg
Molecular Formula C21H16Cl2N2
Molecular Weight 367.27100
Flash Point 254.4ºC
Exact Mass 366.06900
PSA 15.60000
LogP 5.84970
Index of Refraction 1.644

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ8940000
CHEMICAL NAME :
2-Pyrazoline, 3,5-bis(4-chlorophenyl)-1-phenyl-
CAS REGISTRY NUMBER :
57845-06-4
BEILSTEIN REFERENCE NO. :
0307071
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H16-Cl2-N2
MOLECULAR WEIGHT :
367.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 56,129,1987

 Synthetic Route

~91%

3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole Structure

3,5-bis(4-chlor...

CAS#:57845-06-4

Literature: Zhu, Xingyi; Li, Zhenhua; Jin, Can; Xu, Li; Wu, Qianqian; Su, Weike Green Chemistry, 2009 , vol. 11, # 2 p. 163 - 165

~93%

3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole Structure

3,5-bis(4-chlor...

CAS#:57845-06-4

Literature: Safaei-Ghomi; Bamoniri; Soltanian-Telkabadi Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 7 p. 892 - 896

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3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole Structure

3,5-bis(4-chlor...

CAS#:57845-06-4

Literature: Sivakumar, Ponnurengam Malliappan; Ganesan, Suresh; Veluchamy, Prabhawathi; Doble, Mukesh Chemical Biology and Drug Design, 2010 , vol. 76, # 5 p. 407 - 411

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3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole Structure

3,5-bis(4-chlor...

CAS#:57845-06-4

Literature: Safaei-Ghomi; Bamoniri; Soltanian-Telkabadi Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 7 p. 892 - 896

~%

3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole Structure

3,5-bis(4-chlor...

CAS#:57845-06-4

Literature: Safaei-Ghomi; Bamoniri; Soltanian-Telkabadi Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 7 p. 892 - 896

~%

3,5-bis(4-chlorophenyl)-2-phenyl-3,4-dihydropyrazole Structure

3,5-bis(4-chlor...

CAS#:57845-06-4

Literature: Ilford Ltd. Patent: GB669591 , 1949 ;
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