Xantocillin
Modify Date: 2026-07-02 02:32:59
Xantocillin structure
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Common Name | Xantocillin | ||
|---|---|---|---|---|
| CAS Number | 580-74-5 | Molecular Weight | 288.30 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H12N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of XantocillinXanthocillin is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway[1]. |
Summary: Xantocillin, also known as 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene, has a CAS number of 580-74-5. Its molecular formula is C18H12N2O2 and molecular weight is 288.30. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Xanthocillin is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway[1]. |
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| Related Catalog | |
| In Vitro | Xantocillin (SD118-xanthocillin X (1)) (6.9-55.56 µM; 48 hours) has a significant inhibitory effect on the proliferation of HepG2 cells with an IC50 of 22.88 ± 4.76 µM[1]. Xantocillin (SD118-xanthocillin X (1)) (24.3 µM; 12-48 hours) increases the expression of the autophagy-related genes, LC3, and Beclin 1[1]. Cell Proliferation Assay[1] Cell Line: HepG2 cells Concentration: 6.9 µM, 13.89 µM, 27.78 µM, 55.56 µM Incubation Time: 48 hours Result: A concentration-dependent inhibitory effect on cellular growth in the HepG2 cells with the IC50 of 22.88 ± 4.76 µM. Western Blot Analysis[1] Cell Line: HepG2 cells Concentration: 24.3 µM Incubation Time: 12 hours, 24 hours, 48 hours Result: Increased the expression of the autophagy-related genes, LC3, and Beclin 1. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C18H12N2O2 |
|---|---|
| Molecular Weight | 288.30 |
| Exact Mass | 288.09000 |
| PSA | 40.46000 |
| LogP | 2.77980 |
| InChIKey | YBMVKDUTYAGKEW-WHYMJUELSA-N |
| SMILES | [C-]#[N+]C(=Cc1ccc(O)cc1)C(=Cc1ccc(O)cc1)[N+]#[C-] |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| XANTHOCILLINX |
| XANTHOCILINX |
| Brevicide-x |
| Ophthocillin |
| 1,4-Bis-(4-hydroxy-phenyl)-2,3-diisocyan-buta-1,3-dien |
| Xanthocillin |
| Xantocillin |
| 1,4-bis-(4-hydroxy-phenyl)-2,3-diisocyano-buta-1,3-diene |
| Brevicid |
| Brevicide |
| Ethylene isocyanide,bis(p-hydroxybenzylidene) |
| (1Z,3Z)-2,3-diisocyano-1,4-bis(4-hydroxyphenyl)buta-1,3-diene |
| Trianthil |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: Polar surface area (PSA) of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is 40.46000. |
| Q: What is the English name of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: The English name of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene. |
| Q: What is the molecular weight of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: Molecular weight of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is 288.30. |
| Q: What is the LogP of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: LogP of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is 2.77980. |
| Q: What is the CAS number of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: CAS number of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is 580-74-5. |
| Q: What English synonyms does 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene have? |
| A: English synonyms of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene: XANTHOCILLINX, XANTHOCILINX, Brevicide-x, Ophthocillin, 1,4-Bis-(4-hydroxy-phenyl)-2,3-diisocyan-buta-1,3-dien, Xanthocillin, Xantocillin, 1,4-bis-(4-hydroxy-phenyl)-2,3-diisocyano-buta-1,3-diene, Brevicid, Brevicide, Ethylene isocyanide,bis(p-hydroxybenzylidene), (1Z,3Z)-2,3-diisocyano-1,4-bis(4-hydroxyphenyl)buta-1,3-diene, Trianthil. |
| Q: What is the InChIKey of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: InChIKey of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is YBMVKDUTYAGKEW-WHYMJUELSA-N. |
| Q: What is the molecular formula of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: Molecular formula of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is C18H12N2O2. |
| Q: What is the SMILES notation of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: SMILES notation of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene is [C-]#[N+]C(=Cc1ccc(O)cc1)C(=Cc1ccc(O)cc1)[N+]#[C-]. |
| Q: What are the uses of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene? |
| A: Main uses of 1,4-Di-p-oxyphenyl-2,3-di-isonitrilo-1,3-butadiene: Xanthocillin is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway[1]. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |