UK-500001

Modify Date: 2024-02-07 23:21:34

UK-500001 Structure
UK-500001 structure
Common Name UK-500001
CAS Number 582332-31-8 Molecular Weight 499.482
Density 1.4±0.1 g/cm3 Boiling Point 632.2±55.0 °C at 760 mmHg
Molecular Formula C26H24F3N3O4 Melting Point N/A
MSDS N/A Flash Point 336.1±31.5 °C

 Use of UK-500001


A potent, selective phosphodiesterase 4 (PDE4) inhibitor with IC50 of 26.1, 22.8, 21 and 0.28 nM for PDE4A4, PDE4B2, PDE4C2 and PDE4D3, respectively.

 Names

Name UK-500001
Synonym More Synonyms

 UK-500001 Biological Activity

Description A potent, selective phosphodiesterase 4 (PDE4) inhibitor with IC50 of 26.1, 22.8, 21 and 0.28 nM for PDE4A4, PDE4B2, PDE4C2 and PDE4D3, respectively.
References References 1. Moretto N, et al. J Pharmacol Exp Ther. 2015 Mar;352(3):559-67. 2. Vestbo J, et al. Eur Respir J. 2009 May;33(5):1039-44. View Related Products by Target Phosphodiesterase (PDE)

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 632.2±55.0 °C at 760 mmHg
Molecular Formula C26H24F3N3O4
Molecular Weight 499.482
Flash Point 336.1±31.5 °C
Exact Mass 499.171906
LogP 5.12
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.619

 Synonyms

2-(3,4-Difluorophenoxy)-5-fluoro-N-{cis-4-[(2-hydroxy-5-methylbenzoyl)amino]cyclohexyl}nicotinamide
3-Pyridinecarboxamide, 2-(3,4-difluorophenoxy)-5-fluoro-N-[cis-4-[(2-hydroxy-5-methylbenzoyl)amino]cyclohexyl]-
YOG0PR3Q8J
UK-500001
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