Meranzin hydrate

Modify Date: 2024-01-06 12:38:30

Meranzin hydrate structure	Common Name	Meranzin hydrate
	CAS Number	5875-49-0	Molecular Weight	278.300
	Density	1.3±0.1 g/cm3	Boiling Point	500.5±50.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₁₈O₅	Melting Point	130-131°C
	MSDS	USA	Flash Point	188.3±23.6 °C
	Symbol	GHS09	Signal Word	Warning

Use of Meranzin hydrate

Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects[1][2].

Name	Meranzin hydrate
Synonym	More Synonyms

Description	Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Huang X, et al. Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from Chaihu-Shugan-San. PLoS One. 2014 Nov 26;9(11):e113819. [2]. Li L, et al. Chaihu-Shugan-San and absorbed meranzin hydrate induce anti-atherosclerosis and behavioral improvements in high-fat diet ApoE-/- mice via anti-inflammatory and BDNF-TrkB pathway. Biomed Pharmacother. 2019 Jul;115:108893.

Description

Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects[1][2].

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Huang X, et al. Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from Chaihu-Shugan-San. PLoS One. 2014 Nov 26;9(11):e113819.

[2]. Li L, et al. Chaihu-Shugan-San and absorbed meranzin hydrate induce anti-atherosclerosis and behavioral improvements in high-fat diet ApoE-/- mice via anti-inflammatory and BDNF-TrkB pathway. Biomed Pharmacother. 2019 Jul;115:108893.

Density	1.3±0.1 g/cm3
Boiling Point	500.5±50.0 °C at 760 mmHg
Melting Point	130-131°C
Molecular Formula	C₁₅H₁₈O₅
Molecular Weight	278.300
Flash Point	188.3±23.6 °C
Exact Mass	278.115417
PSA	79.90000
LogP	0.61
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.580
Storage condition	?20°C

Meranzin hydrate MSDS(Chinese)

Symbol	GHS09
Signal Word	Warning
Hazard Statements	H410
Precautionary Statements	P273-P501
Hazard Codes	N
Risk Phrases	50
Safety Phrases	61
RIDADR	UN 3077 9 / PGIII

Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from Chaihu-Shugan-San.

PLoS ONE 9(11) , e113819, (2014)

Meranzin hydrate (MH), an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), was first isolated in our laboratory and was found to possess anti-depression...

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