5875-49-0

5875-49-0 structure

Name: Meranzin hydrate
Chemical Name: Meranzin hydrate
CAS Number: 5875-49-0
Molecular Formula: C₁₅H₁₈O₅
Molecular Weight: 278.300
Catalog: Natural product Coumarin
Create Date: 2016-08-05 23:58:16
Modify Date: 2024-01-06 12:38:30
Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects[1][2].

Name	Meranzin hydrate
Synonyms	2H-1-Benzopyran-2-one, 8-[(2S)-2,3-dihydroxy-3-methylbutyl]-7-methoxy- 8-(2,3-Dihydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-one 2H-1-Benzopyran-2-one, 8-(2,3-dihydroxy-3-methylbutyl)-7-methoxy- 8-[(2S)-2,3-Dihydroxy-3-methylbutyl]-7-methoxy-2H-chromen-2-one

Description	Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Huang X, et al. Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from Chaihu-Shugan-San. PLoS One. 2014 Nov 26;9(11):e113819. [2]. Li L, et al. Chaihu-Shugan-San and absorbed meranzin hydrate induce anti-atherosclerosis and behavioral improvements in high-fat diet ApoE-/- mice via anti-inflammatory and BDNF-TrkB pathway. Biomed Pharmacother. 2019 Jul;115:108893.