(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide

Modify Date: 2024-01-09 15:59:31

(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide Structure
(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide structure
Common Name (E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide
CAS Number 58754-46-4 Molecular Weight 348.48100
Density 1.096g/cm3 Boiling Point 536.4ºC at 760 mmHg
Molecular Formula C23H28N2O Melting Point N/A
MSDS N/A Flash Point 278.2ºC

 Use of (E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide


Iferanserin (S-MPEC) is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin has the potential for internal hemorrhoid disease treatment[1].

 Names

Name iferanserin

  Biological Activity

Description Iferanserin (S-MPEC) is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin has the potential for internal hemorrhoid disease treatment[1].
Related Catalog
Target

5-HT2A Receptor

In Vitro An intra-anal ointment application of Iferanserin might modify the vascular effects occurring in hemorrhoid disease and thereby reduce or eliminate the most frequently occurring symptoms of hemorrhoid disease[1].
References

[1]. Herold A, et al. Intra-anal Iferanserin 10 mg BID for hemorrhoid disease: a prospective, randomized, double-blind, placebo-controlled trial. Clin Ther. 2012 Feb;34(2):329-40.

 Chemical & Physical Properties

Density 1.096g/cm3
Boiling Point 536.4ºC at 760 mmHg
Molecular Formula C23H28N2O
Molecular Weight 348.48100
Flash Point 278.2ºC
Exact Mass 348.22000
PSA 32.34000
LogP 4.76630
Index of Refraction 1.61

 Synthetic Route

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(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide Structure

(E)-N-[2-[2-[(2...

CAS#:58754-46-4

Literature: SAM AMER and CO., INC.; AMER, Moh, Samir Patent: WO2012/26914 A1, 2012 ; Location in patent: Page/Page column 13 ; WO 2012/026914 A1

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(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide Structure

(E)-N-[2-[2-[(2...

CAS#:58754-46-4

Literature: SAM AMER and CO., INC.; AMER, Moh, Samir Patent: WO2012/26914 A1, 2012 ; WO 2012/026914 A1

~%

(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide Structure

(E)-N-[2-[2-[(2...

CAS#:58754-46-4

Literature: SAM AMER and CO., INC.; AMER, Moh, Samir Patent: WO2012/26914 A1, 2012 ; WO 2012/026914 A1

~%

(E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide Structure

(E)-N-[2-[2-[(2...

CAS#:58754-46-4

Literature: SAM AMER and CO., INC.; AMER, Moh, Samir Patent: WO2012/26914 A1, 2012 ; WO 2012/026914 A1
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