Monomyristin

Modify Date: 2024-01-08 10:43:40

Monomyristin Structure
Monomyristin structure
Common Name Monomyristin
CAS Number 589-68-4 Molecular Weight 302.449
Density 1.0±0.1 g/cm3 Boiling Point 424.8±25.0 °C at 760 mmHg
Molecular Formula C17H34O4 Melting Point 68-70ºC
MSDS USA Flash Point 141.3±16.7 °C

 Use of Monomyristin


1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].

 Names

Name 2,3-Dihydroxypropyl tetradecanoate
Synonym More Synonyms

 Monomyristin Biological Activity

Description 1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].
Related Catalog
Target

IC50: 18 μM (FAAH)[2]

References

[1]. Shimada H, et al. Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens). J Nat Prod. 1997 Apr;60(4):417-8.

[2]. Vandevoorde S, et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochem Biophys Res Commun. 2005 Nov 11;337(1):104-9.

[3]. Jumina, et al. Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents. Molecules. 2018 Nov 29;23(12). pii: E3141

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 424.8±25.0 °C at 760 mmHg
Melting Point 68-70ºC
Molecular Formula C17H34O4
Molecular Weight 302.449
Flash Point 141.3±16.7 °C
Exact Mass 302.245697
PSA 66.76000
LogP 5.10
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.468

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
HS Code 2915900090

 Synthetic Route

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Articles3

More Articles
Adsorption of 1-Monoglycerides at the Hexane/Water Interface.

J. Colloid. Interface Sci. 220 , 374-379, (1999)

The interfacial tension of a hexane solution of 1-monolaurin against water was measured as a function of temperature and concentration under atmospheric pressure. The thermodynamic quantity changes as...

Structure of nonionic surfactant (glycerol alpha-monomyristate) micelles in organic solvents: a SAXS study.

J. Phys. Chem. B 113 , 6290-6298, (2009)

In this paper we present the study of reverse micellar aggregates formed by glycerol alpha-monomyristate (C(14)G(1)) in different organic solvents. We have investigated the structure (mainly shape and...

Absorption properties of micellar lipid metabolites into Caco2 cells.

Lipids 42 , 613-619, (2007)

To elucidate the absorption characteristics of dietary lipids in the human intestine, we investigated the cellular uptake of lipid metabolites using a differential monolayer of the Caco2 cells. As lip...

 Synonyms

Myristic acid 1-monoglyceride
Tetradecanoic acid, 2,3-dihydroxypropyl ester
MFCD00046760
2,3-Dihydroxypropyl myristate
1-monomyristoylglycerol
UNII:SMJ2192F1R
rac-Glycerol 1-myristate
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Monomyristin suppliers


Price: ¥608.4/1g

Reference only. check more Monomyristin price