6-Oxoprostaglandin F1α

Modify Date: 2025-08-25 16:31:32

6-Oxoprostaglandin F1α Structure
6-Oxoprostaglandin F1α structure
Common Name 6-Oxoprostaglandin F1α
CAS Number 58962-34-8 Molecular Weight 370.480
Density 1.2±0.1 g/cm3 Boiling Point 575.3±50.0 °C at 760 mmHg
Molecular Formula C20H34O6 Melting Point N/A
MSDS N/A Flash Point 315.8±26.6 °C

 Use of 6-Oxoprostaglandin F1α


6-keto Prostaglandin F1α is an endogenous metabolite present in Cerebrospinal_Fluid, Urine and Blood that can be used for the research of Meningitis, Rheumatoid Arthritis and Cardiopulmonary Resuscitation[1][2][3][4].

 Names

Name 6-oxo-prostaglandin F1α
Synonym More Synonyms

 6-Oxoprostaglandin F1α Biological Activity

Description 6-keto Prostaglandin F1α is an endogenous metabolite present in Cerebrospinal_Fluid, Urine and Blood that can be used for the research of Meningitis, Rheumatoid Arthritis and Cardiopulmonary Resuscitation[1][2][3][4].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Westcott JY, et al. Eicosanoids in human ventricular cerebrospinal fluid following severe brain injury. Prostaglandins. 1987 Dec;34(6):877-87.  

[3]. Laitinen O, et al. Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis. Clin Rheumatol. 1983 Dec;2(4):401-6.  

[4]. Strohmenger HU, et al. Concentrations of prolactin and prostaglandins during and after cardiopulmonary resuscitation. Crit Care Med. 1995 Aug;23(8):1347-55.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 575.3±50.0 °C at 760 mmHg
Molecular Formula C20H34O6
Molecular Weight 370.480
Flash Point 315.8±26.6 °C
Exact Mass 370.235535
PSA 115.06000
LogP 0.93
Vapour Pressure 0.0±3.6 mmHg at 25°C
Index of Refraction 1.561
InChIKey KFGOFTHODYBSGM-ZUNNJUQCSA-N
SMILES CCCCCC(O)C=CC1C(O)CC(O)C1CC(=O)CCCCC(=O)O

 Safety Information

Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport

 Synthetic Route

 Synonyms

Prost-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9α,11α,13E,15S)-
6-Oxoprostaglandin F1α
6-KETO-PROSTAGLANDIN F1ALPHA
6-OXO-9ALPHA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID
Prosta-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9α,11α,13E,15S)-
6-oxo-prostaglandin F1alpha
6-Oxoprostaglandin F1alpha
6-KETOPROSTAGLANDIN F1A
(9α,11α,13E,15S)-9,11,15-Trihydroxy-6-oxoprost-13-en-1-oic acid
6-Keto Prostaglandin
7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-6-oxoheptanoic acid
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