3-Hydroxy-3-(2H3)methylpentanedioic acid
Modify Date: 2024-01-21 10:53:41
3-Hydroxy-3-(2H3)methylpentanedioic acid structure
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Common Name | 3-Hydroxy-3-(2H3)methylpentanedioic acid | ||
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| CAS Number | 59060-36-5 | Molecular Weight | 165.159 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 354.3±32.0 °C at 760 mmHg | |
| Molecular Formula | C6H7D3O5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 182.2±21.6 °C | |
Use of 3-Hydroxy-3-(2H3)methylpentanedioic acidMeglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol. |
| Name | 3-hydroxy-3-methyl-d3-pentanedioic acid |
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| Synonym | More Synonyms |
| Description | Meglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 354.3±32.0 °C at 760 mmHg |
| Molecular Formula | C6H7D3O5 |
| Molecular Weight | 165.159 |
| Flash Point | 182.2±21.6 °C |
| Exact Mass | 165.071655 |
| PSA | 94.83000 |
| LogP | -2.33 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.515 |
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3-Hydroxy-3-(2H... CAS#:59060-36-5 |
| Literature: Gill, Harjit K.; Smith, Roland W.; Whiting, Donald A. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 11 p. 2989 - 2993 |
![4-hydroxy-4-[2H3]methylhepta-1,6-diene structure](https://image.chemsrc.com/caspic/132/59060-35-4.png)
| Precursor 1 | |
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| DownStream 2 | |
CAS#:115135-38-1
CAS#:61219-76-9| 3-hydroxy-3-<2H3>methylglutaric acid |
| 3-Hydroxy-3-(H)methylpentanedioic acid |
| 3-hydroxy-3-<methyl-2H3>pentane-1,5-dioic acid |
| 3-Hydroxy-3-trideuteromethylglutarsaeure |
| 3-Hydroxy-3-<3.4.5-trimethoxy-phenyl>-3-<3.4-methylendioxy-phenyl>-propionsaeure-ethylester |
| Pentanedioic acid, 3-hydroxy-3-(methyl-d)- |