3-hydroxy-3-methylglutaric acid
3-hydroxy-3-methylglutaric acid structure
|
Common Name | 3-hydroxy-3-methylglutaric acid | ||
|---|---|---|---|---|
| CAS Number | 503-49-1 | Molecular Weight | 162.14100 | |
| Density | 1.417 g/cm3 | Boiling Point | 120 °C / 13mmHg | |
| Molecular Formula | C6H10O5 | Melting Point | 105-108 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 182.2ºC | |
Use of 3-hydroxy-3-methylglutaric acidMeglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol. |
| Name | 3-hydroxy-3-methylglutaric acid |
|---|---|
| Synonym | More Synonyms |
| Description | Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol. |
|---|---|
| Related Catalog |
| Density | 1.417 g/cm3 |
|---|---|
| Boiling Point | 120 °C / 13mmHg |
| Melting Point | 105-108 °C(lit.) |
| Molecular Formula | C6H10O5 |
| Molecular Weight | 162.14100 |
| Flash Point | 182.2ºC |
| Exact Mass | 162.05300 |
| PSA | 94.83000 |
| Index of Refraction | 1.512 |
| Storage condition | −20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | MA3753000 |
| HS Code | 2918199090 |
| Precursor 9 | |
|---|---|
| DownStream 10 | |
CAS#:7564-64-9
CAS#:89622-82-2
CAS#:7440-44-0
CAS#:25201-40-5
CAS#:674-26-0![7-O-[hydrogen (3S)-3-hydroxy-3-methylglutaryl]retronecanol Structure](https://image.chemsrc.com/caspic/249/88205-12-3.png)
CAS#:88205-12-3
CAS#:34695-32-4
CAS#:81943-18-2
CAS#:73489-84-6
CAS#:476-56-2
CAS#:2387-23-7
CAS#:481-74-3
CAS#:19115-49-2
CAS#:87894-65-3
CAS#:150-97-0| HS Code | 2918199090 |
|---|---|
| Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
|
NMR spectroscopic studies on the late onset form of 3-methylglutaconic aciduria type I and other defects in leucine metabolism.
NMR Biomed. 19(2) , 271-8, (2006) A diagnosis of 3-methylglutaconic aciduria type I (OMIM: 250950) based on elevated urinary excretion of 3-methylglutaconic acid (3MGA), 3-methylglutaric acid (3MG) and 3-hydroxyisovaleric acid (3HIVA)... |
|
|
Unimolecular reaction chemistry of a charge-tagged beta-hydroxyperoxyl radical.
Phys. Chem. Chem. Phys. 16(45) , 24954-64, (2014) β-Hydroxyperoxyl radicals are formed during atmospheric oxidation of unsaturated volatile organic compounds such as isoprene. They are intermediates in the combustion of alcohols. In these environment... |
|
|
Mitochondrial DNA depletion associated with partial complex II and IV deficiencies and 3-methylglutaconic aciduria.
J. Child Neurol. 16(2) , 136-8, (2001) We report a patient with mitochondrial DNA depletion, partial complex II and IV deficiencies, and 3-methylglutaconic aciduria. Complex II deficiency has not been previously observed in mitochondrial D... |
| EINECS 207-971-1 |
| MFCD00002712 |
| 3-hydroxy-3-methylpentanedioic acid |
| 3-Hydroxy-3-Methylglutaric Acid |
| Meglutol |