Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate

Modify Date: 2024-01-02 10:06:34

Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate Structure
Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate structure
Common Name Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate
CAS Number 5909-24-0 Molecular Weight 232.687
Density 1.4±0.1 g/cm3 Boiling Point 335.7±22.0 °C at 760 mmHg
Molecular Formula C8H9ClN2O2S Melting Point 60-63 °C(lit.)
MSDS Chinese USA Flash Point 156.8±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate


Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 2-Methylthio-4-Chloro-5-Ethoxycarbonylpyrimidine
Synonym More Synonyms

  Biological Activity

Description Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 335.7±22.0 °C at 760 mmHg
Melting Point 60-63 °C(lit.)
Molecular Formula C8H9ClN2O2S
Molecular Weight 232.687
Flash Point 156.8±22.3 °C
Exact Mass 232.007324
PSA 77.38000
LogP 2.55
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.568
Storage condition Keep Cold

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933599090

 Synthetic Route

~77%

Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate Structure

Ethyl 4-chloro-...

CAS#:5909-24-0

Literature: DECIPHERA PHARMACEUTICALS, LLC Patent: WO2006/71940 A2, 2006 ; Location in patent: Page/Page column 354 ; WO 2006/071940 A2

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Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate Structure

Ethyl 4-chloro-...

CAS#:5909-24-0

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 15 p. 1645 - 1648

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors.

Bioorg. Med. Chem. Lett. 18(7) , 2355-61, (2008)

A series of pyrimidinopyridones has been designed, synthesized and shown to be potent and selective inhibitors of the FMS tyrosine kinase. Introduction of an amide substituent at the 6-position of the...

 Synonyms

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
EINECS 227-619-0
Ethyl 4-chloro-2-(methylsulfanyl)-5-pyrimidinecarboxylate
ethyl 4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxylate
Ethyl 4-chloro-2-(methylthio)-5-pyrimidinecarboxylate
MFCD00006085
4-chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
4-chloro-5-carbethoxy-2-methylthiopyrimidine
5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-, ethyl ester
Ethyl-4-chlor-2-(methylsulfanyl)pyrimidin-5-carboxylat
5-Pyrimidinecarboxylic acid, 4-chloro-2- (methylthio)-, ethyl ester
ethyl 4-chloro-2-methylsulfanylpyrimidine-5-carboxylate
ethyl4-chloro-2-(methylthio)pyrimidine-5-carboxylate
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