Name | 11R-VIVIT | CAS# | 592517-80-1 | |
---|---|---|---|---|
Price | ¥550.0/10mg ¥900.0/25mg ¥1700.0/100mg ¥220.0/10ml | Purity | 98.0% | |
Stocking Period |
1 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-11r-vivit.html |
Detail
Product Information
11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. |