(Chloromethyl)(trimethoxy)silane

Modify Date: 2024-01-02 19:31:53

(Chloromethyl)(trimethoxy)silane Structure
(Chloromethyl)(trimethoxy)silane structure
 Common Name (Chloromethyl)(trimethoxy)silane
CAS Number 5926-26-1 Molecular Weight 170.667
Density 1.1±0.1 g/cm3 Boiling Point 132.2±13.0 °C at 760 mmHg
Molecular Formula C4H11ClO3Si Melting Point N/A
MSDS Chinese USA Flash Point 30.1±12.0 °C
Symbol GHS02
GHS02		 Signal Word Danger

 Names

Name (Chloromethyl)trimethoxysilane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 132.2±13.0 °C at 760 mmHg
Molecular Formula C4H11ClO3Si
Molecular Weight 170.667
Flash Point 30.1±12.0 °C
Exact Mass 170.016602
PSA 27.69000
LogP 0.37
Vapour Pressure 11.0±0.2 mmHg at 25°C
Index of Refraction 1.405

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VV2625000
CHEMICAL NAME :
Silane, chloromethyl-trimethoxy-
CAS REGISTRY NUMBER :
5926-26-1
LAST UPDATED :
199806
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H11-Cl-O3-Si
MOLECULAR WEIGHT :
170.69
WISWESSER LINE NOTATION :
G1-SI-O1&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3600 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986

 Safety Information

Symbol GHS02
GHS02
Signal Word Danger
Hazard Statements H225
Precautionary Statements P210
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F
Risk Phrases 11
Safety Phrases S16-S29-S33
RIDADR UN 1993 3/PG 2
WGK Germany 3
Packaging Group II

 Synthetic Route

chloromethyl silyl dichloride structure

chloromethyl si...

CAS#:18170-89-3

Trimethyl orthoformate structure

Trimethyl ortho...

CAS#:149-73-5

~%

(Chloromethyl)(trimethoxy)silane Structure

(Chloromethyl)(...

CAS#:5926-26-1

chloromethyldimethoxysilane structure

chloromethyldim...

CAS#:860465-66-3

Detail
Literature: EP2586784 A1, ; Paragraph 0032 ;
Methanol structure

Methanol

CAS#:67-56-1

chloromethyl silyl dichloride structure

chloromethyl si...

CAS#:18170-89-3

~%

(Chloromethyl)(trimethoxy)silane Structure

(Chloromethyl)(...

CAS#:5926-26-1

chloromethyldimethoxysilane structure

chloromethyldim...

CAS#:860465-66-3

Literature: EP2586783 A1, ; Paragraph 0041 ;
Methanol structure

Methanol

CAS#:67-56-1

chloromethyl silyl dichloride structure

chloromethyl si...

CAS#:18170-89-3

Trimethyl orthoformate structure

Trimethyl ortho...

CAS#:149-73-5

~%

(Chloromethyl)(trimethoxy)silane Structure

(Chloromethyl)(...

CAS#:5926-26-1

Detail
Literature: EP2586783 A1, ; Paragraph 0043 ;
Methanol structure

Methanol

CAS#:67-56-1

1,1,1-Trimethoxyethane structure

1,1,1-Trimethox...

CAS#:1445-45-0

chloromethyl silyl dichloride structure

chloromethyl si...

CAS#:18170-89-3

~%

(Chloromethyl)(trimethoxy)silane Structure

(Chloromethyl)(...

CAS#:5926-26-1

Detail
Literature: EP2586783 A1, ; Paragraph 0047 ;
Methanol structure

Methanol

CAS#:67-56-1

chloromethyl silyl dichloride structure

chloromethyl si...

CAS#:18170-89-3

Trimethyl orthoformate structure

Trimethyl ortho...

CAS#:149-73-5

~%

(Chloromethyl)(trimethoxy)silane Structure

(Chloromethyl)(...

CAS#:5926-26-1

Detail
Literature: EP2586783 A1, ; Paragraph 0046 ;
Methanol structure

Methanol

CAS#:67-56-1

Trichloro(chloromethyl)silane structure

Trichloro(chlor...

CAS#:1558-25-4

~81%

(Chloromethyl)(trimethoxy)silane Structure

(Chloromethyl)(...

CAS#:5926-26-1

Literature: Tacke, Reinhold; Pikies, Jerzy; Linoh, Haryanto; Rohr-Aehle, Regine; Goenne, Sigrid Liebigs Annalen der Chemie, 1987 , p. 51 - 58

 Articles3

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Mesoporous Silica Nanoparticles with pH-Sensitive Nanovalves for Delivery of Moxifloxacin Provide Improved Treatment of Lethal Pneumonic Tularemia.

ACS Nano 9 , 10778-89, (2015)

We have optimized mesoporous silica nanoparticles (MSNs) functionalized with pH-sensitive nanovalves for the delivery of the broad spectrum fluoroquinolone moxifloxacin (MXF) and demonstrated its effi...

Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves.

J. Am. Chem. Soc. 132(36) , 12690-7, (2010)

Mesoporous silica nanoparticles (MSNP) have proven to be an extremely effective solid support for controlled drug delivery on account of the fact that their surfaces can be easily functionalized in or...

Space-confined click reactions in hierarchically organized silica monoliths. Keppeler M and Hüsing N

New J. Chem. 35(3) , 681-690, (2011)

 Synonyms

G1-SI-O1&O1&O1
Chloromethyltrimethoxysilane
Silane, (chloromethyl)trimethoxy-
(Chloromethyl)(trimethoxy)silane
MFCD00468107
chloromethyl(trimethoxy)silane
Chloromethyl Trimethoxysilane
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Related Compounds: More...
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Chemsrc provides (Chloromethyl)(trimethoxy)silane(CAS#:5926-26-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of (Chloromethyl)(trimethoxy)silane are included as well.>> amp version: (Chloromethyl)(trimethoxy)silane

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