Meptazinol HCl
Meptazinol HCl structure
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Common Name | Meptazinol HCl | ||
|---|---|---|---|---|
| CAS Number | 59263-76-2 | Molecular Weight | 269.810 | |
| Density | N/A | Boiling Point | 354.8ºC at 760 mmHg | |
| Molecular Formula | C15H24ClNO | Melting Point | 250-252ºC | |
| MSDS | Chinese USA | Flash Point | 160.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Meptazinol HClMeptazinol Hcl(WY-22811 Hcl) is a unique centrally active opioid analgesic. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Meptazinol Hydrochloride |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Boiling Point | 354.8ºC at 760 mmHg |
|---|---|
| Melting Point | 250-252ºC |
| Molecular Formula | C15H24ClNO |
| Molecular Weight | 269.810 |
| Flash Point | 160.6ºC |
| Exact Mass | 269.154633 |
| PSA | 23.47000 |
| LogP | 3.89560 |
| InChIKey | MPJUSISYVXABBH-UHFFFAOYSA-N |
| SMILES | CCC1(c2cccc(O)c2)CCCCN(C)C1.Cl |
| Storage condition | Desiccate at +4°C |
| Water Solubility | H2O: >10mg/mL |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: Bradley; Cavalla; Edington; et al. European Journal of Medicinal Chemistry, 1980 , vol. 15, # 4 p. 375 - 385 |
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
|
~%
Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
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Meptazinol HCl CAS#:59263-76-2 |
| Literature: European Journal of Medicinal Chemistry, , vol. 15, # 4 p. 375 - 385 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 1 | |
CAS#:54340-58-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2942000000 |
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This table lists relevant public references with title, journal and publication metadata for this compound.
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Bis(9)-(-)-nor-meptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice.
Pharmacol. Biochem. Behav. 104 , 138-43, (2013) Alzheimer's disease (AD) is a multifaceted neurodegenerative disorder which is characterized by the progressive deterioration of cognition and the emergence of behavioral and psychological symptoms in... |
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Reflex activity caused by laryngoscopy and intubation is obtunded differently by meptazinol, nalbuphine and fentanyl.
Eur. J. Anaesthesiol. 24(1) , 53-8, (2007) To evaluate the different potencies of several opioids in obtunding reflex mechanisms of laryngoscopy and intubation.Three groups of patients (each n = 25, ASA 1-2) undergoing elective plastic surgery... |
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Lack of sensitization during place conditioning in rats is consistent with the low abuse potential of tramadol.
Neurosci. Lett. 329(1) , 25-8, (2002) Based on the recent finding that tramadol (TRAM) produces conditioned place preference (CPP) and dopamine release in the nucleus accumbens, it was suggested that the abuse liability of TRAM may be gre... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Phenol, 3-(3-ethylhexahydro-1-methyl-1H-azepin-3-yl)-, hydrochloride (1:1) |
| 3-(3-Ethyl-1-methylazepan-3-yl)phenol hydrochloride (1:1) |
| 3-(3-ethyl-1-methylazepan-3-yl)phenol,hydrochloride |
| 3-(3-Ethyl-1-methyl-3-azepanyl)phenol hydrochloride (1:1) |
| UNII:T62FQ4ZCPA |
| MEPTAZINOL HYDROCHLORIDE |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of Meptazinol Hydrochloride? |
| A: InChIKey of Meptazinol Hydrochloride is MPJUSISYVXABBH-UHFFFAOYSA-N. |
| Q: What is the molecular formula of Meptazinol Hydrochloride? |
| A: Molecular formula of Meptazinol Hydrochloride is C15H24ClNO. |
| Q: What is the English name of Meptazinol Hydrochloride? |
| A: The English name of Meptazinol Hydrochloride is Meptazinol Hydrochloride. |
| Q: What is the polar surface area (PSA) of Meptazinol Hydrochloride? |
| A: Polar surface area (PSA) of Meptazinol Hydrochloride is 23.47000. |
| Q: What is the SMILES notation of Meptazinol Hydrochloride? |
| A: SMILES notation of Meptazinol Hydrochloride is CCC1(c2cccc(O)c2)CCCCN(C)C1.Cl. |
| Q: What is the CAS number of Meptazinol Hydrochloride? |
| A: CAS number of Meptazinol Hydrochloride is 59263-76-2. |
| Q: What are the upstream materials of Meptazinol Hydrochloride? |
| A: Related upstream materials(CAS) of Meptazinol Hydrochloride: 71556-73-5;105-60-2;2556-73-2;766-51-8;71556-70-2;71592-44-4;71592-43-3;71556-72-4;50-00-0;59263-75-1. |
| Q: How is the water solubility of Meptazinol Hydrochloride? |
| A: Water solubility of Meptazinol Hydrochloride: H2O: >10mg/mL. |
| Q: What is the melting point of Meptazinol Hydrochloride? |
| A: Melting point of Meptazinol Hydrochloride is 250-252ºC. |
| Q: What are the downstream products of Meptazinol Hydrochloride? |
| A: Related downstream products(CAS) of Meptazinol Hydrochloride: 54340-58-8. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |