Monotropein

Modify Date: 2024-01-02 14:17:53

Monotropein Structure
Monotropein structure
Common Name Monotropein
CAS Number 5945-50-6 Molecular Weight 390.339
Density 1.7±0.1 g/cm3 Boiling Point 717.6±60.0 °C at 760 mmHg
Molecular Formula C16H22O11 Melting Point N/A
MSDS N/A Flash Point 262.0±26.4 °C

 Use of Monotropein


Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model[1].

 Names

Name monotropein
Synonym More Synonyms

 Monotropein Biological Activity

Description Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model[1].
Related Catalog
References

[1]. Wang F, et al.Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes.Int Immunopharmacol. 2014 Dec;23(2):575-80.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 717.6±60.0 °C at 760 mmHg
Molecular Formula C16H22O11
Molecular Weight 390.339
Flash Point 262.0±26.4 °C
Exact Mass 390.116211
PSA 186.37000
LogP -4.43
Vapour Pressure 0.0±5.2 mmHg at 25°C
Index of Refraction 1.686

 Safety Information

Safety Phrases 24/25

 Synthetic Route

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Monotropein Structure

Monotropein

CAS#:5945-50-6

Literature: Archiv der Pharmazie (Weinheim, Germany), , vol. 313, # 8 p. 702 - 708

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,7,7a-tetrahydro-7-hydroxy-7-(hydroxymethyl)-, (1S,4aS,7R,7aS)-
(1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid
Morinda officinalis How
(1S,4aS,7R,7aS)-1-(β-D-Glucopyranosyloxy)-7-hydroxy-7-(hydroxymethyl)-1,4a,7,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid
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