N-Methylthiourea

Modify Date: 2026-07-01 15:56:38

N-Methylthiourea structure	Common Name	N-Methylthiourea
	CAS Number	598-52-7	Molecular Weight	90.147
	Density	1.1±0.1 g/cm3	Boiling Point	141.1±23.0 °C at 760 mmHg
	Molecular Formula	C₂H₆N₂S	Melting Point	118-121 °C(lit.)
	MSDS	Chinese USA	Flash Point	39.1±22.6 °C
	Symbol	GHS06	Signal Word	Danger

Summary: N-甲基硫脲, Chinese name N-Methylthiourea, CAS number 598-52-7, molecular formula C2H6N2S, molecular weight 90.147. Appearance: white crystalline powder, melting point 118-121°C, boiling point 141.1±23.0°C, density 1.1±0.1g/cm3. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	N-Methylthiourea
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.1±0.1 g/cm3
Boiling Point	141.1±23.0 °C at 760 mmHg
Melting Point	118-121 °C(lit.)
Molecular Formula	C₂H₆N₂S
Molecular Weight	90.147
Flash Point	39.1±22.6 °C
Exact Mass	90.025169
PSA	70.14000
LogP	-0.71
Vapour Pressure	6.0±0.3 mmHg at 25°C
Index of Refraction	1.565
InChIKey	KQJQICVXLJTWQD-UHFFFAOYSA-N
SMILES	CNC(N)=S

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

N-Methylthiourea MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YT9000000

CHEMICAL NAME :: Urea, 1-methyl-2-thio-

CAS REGISTRY NUMBER :: 598-52-7

LAST UPDATED :: 199709

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C2-H6-N2-S

MOLECULAR WEIGHT :: 90.16

WISWESSER LINE NOTATION :: SUYZM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 35,409,1980

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 23,335,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2885 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1419,1974 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 500 mg/kg

SEX/DURATION :: female 12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - gastrointestinal system

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 23,335,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 200 mg/kg

SEX/DURATION :: female 14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 26(1),19A,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 250 mg/kg

SEX/DURATION :: female 14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 23,335,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 400 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 28,38A,1983

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1 gm/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: 49WEAZ "Pesticide Chemistry: Human Welfare and the Environment, Proceedings of the International Congress of Pesticide Chemistry, 5th, Kyoto, Japan, 1982," Miyamoto, J. and Kearney, P.C., eds., Oxford, UK, Pergamon Press Ltd., 1983 Volume(issue)/page/year: 3,479,1983

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300
Precautionary Statements	P264-P301 + P310
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25
Safety Phrases	S36/37/39-S45
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS	YT9000000
Packaging Group	II
Hazard Class	6.1
HS Code	2930909090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:556-61-6 Methyl isothioc... CAS#:37929-27-4 USAF K-1338 CAS#:27406-60-6 6-hydroxy-1,4,4... CAS#:75039-91-7 ethyl 3-(N-meth...
CAS#:13037-11-1 Carbamodithioic... CAS#:52664-26-3 ethyl N-methylc... CAS#:38475-06-8 N,N''-dimethyl-... CAS#:16486-25-2 N-(methylcarbam...
CAS#:625-57-0 O-Ethyl thiocar... CAS#:74-89-5 methylamine
DownStream 9
CAS#:463-56-9 thiocyanic acid CAS#:7664-41-7 Ammonia CAS#:74-89-5 methylamine CAS#:108249-21-4 amino(methylimi...
CAS#:5422-44-6 1-Methyl-1H-tet... CAS#:41306-45-0 1,2-Dimethyliso... CAS#:25433-05-0 3,4,5-trimethyl... CAS#:2933-32-6 4(5H)-Thiazolon...
CAS#:598-50-5 1-Methylurea

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury.

PLoS ONE 10(3) , e0119918, (2015)

Lipopolysaccharide (LPS) derived from the outer membrane of gram-negative bacteria induces acute lung injury (ALI) in mice. This injury is associated with lung edema, inflammation, diffuse alveolar da...

Metabolism of 4-[1-(2-fluoro-4-biphenylyl)ethyl]-2-methylaminothiazole (SM-8849) in rats.

Eur. J. Drug Metab. Pharmacokinet. 22(1) , 25-33, (1997)

Metabolism of 4-[1-(2-fluoro-4-biphenylyl)ethyl]-2-methylaminothiazole (SM-8849), a novel immunomodulatory agent, in rats was investigated. By co-chromatography with authentic samples, desmethylated (...

[Proper use of noxythiolin: an experimental rat study on interaction with lactic acid].

Therapie. 35(3) , 409-12, (1980)

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose

Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose

Total 2, Current Page 1 of 1

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD00004938

EINECS 209-936-6

1-Methylthiourea

methylthiourea

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of N-Methylthiourea?

A: CAS number of N-Methylthiourea is 598-52-7.

Q: What is the melting point of N-Methylthiourea?

A: Melting point of N-Methylthiourea is 118-121 °C(lit.).

Q: What is the LogP of N-Methylthiourea?

A: LogP of N-Methylthiourea is -0.71.

Q: What is the molecular formula of N-Methylthiourea?

A: Molecular formula of N-Methylthiourea is C2H6N2S.

Q: What are the upstream materials of N-Methylthiourea?

A: Related upstream materials(CAS) of N-Methylthiourea: 556-61-6;37929-27-4;27406-60-6;75039-91-7;13037-11-1;52664-26-3;38475-06-8;16486-25-2;625-57-0;74-89-5.

Q: What are the downstream products of N-Methylthiourea?

A: Related downstream products(CAS) of N-Methylthiourea: 463-56-9;7664-41-7;74-89-5;108249-21-4;5422-44-6;41306-45-0;25433-05-0;2933-32-6;598-50-5.

Q: What is the InChIKey of N-Methylthiourea?

A: InChIKey of N-Methylthiourea is KQJQICVXLJTWQD-UHFFFAOYSA-N.

Q: What is the boiling point of N-Methylthiourea?

A: Boiling point of N-Methylthiourea is 141.1±23.0 °C at 760 mmHg.

Q: What is the polar surface area (PSA) of N-Methylthiourea?

A: Polar surface area (PSA) of N-Methylthiourea is 70.14000.

Q: What is the molecular weight of N-Methylthiourea?

A: Molecular weight of N-Methylthiourea is 90.147.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: N-Methylthiourea
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-Methylthiourea
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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N-Methylthiourea

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N-MethylthioureaBioassay

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.