(±)-N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine

Modify Date: 2024-01-06 19:47:19

(±)-N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine Structure
(±)-N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine structure
Common Name (±)-N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine
CAS Number 599-54-2 Molecular Weight 219.23500
Density 1.266g/cm3 Boiling Point 551.5ºC at 760mmHg
Molecular Formula C9H17NO5 Melting Point N/A
MSDS N/A Flash Point 287.3ºC

 Use of (±)-N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine


(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice[1].

 Names

Name pantothenic acid
Synonym More Synonyms

  Biological Activity

Description (±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice[1].
Related Catalog
In Vivo (±)-Pantothenic acid (3 × 200 mg/kg; IP, single dosage) blocks VPA-induced decreases in c-Myb and Pim-1 protein expression; reduces the incidence of NTD to 6.8% in VPA-injected CD-1 mice, while incidence of the untreated group is 23.6%[1].
References

[1]. Tahiliani AG, Beinlich CJ. Pantothenic acid in health and disease. Vitam Horm. 1991;46:165-228.

[2]. Dawson JE, et al. Folic acid and pantothenic acid protection against valproic acid-induced neural tube defects in CD-1 mice. Toxicol Appl Pharmacol. 2006 Mar 1;211(2):124-32.

 Chemical & Physical Properties

Density 1.266g/cm3
Boiling Point 551.5ºC at 760mmHg
Molecular Formula C9H17NO5
Molecular Weight 219.23500
Flash Point 287.3ºC
Exact Mass 219.11100
PSA 110.35000

 Safety Information

Hazard Codes Xi
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

DL-Pantothensaeure
(+)-Pantothenic acid
Pantothensaeure
panthothenic acid
DL-Pantothenic acid
3-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]propanoic acid
(+)-Pantothenate