5,7,8-Trimethoxycoumarin
Modify Date: 2024-01-06 11:01:25
5,7,8-Trimethoxycoumarin structure
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Common Name | 5,7,8-Trimethoxycoumarin | ||
|---|---|---|---|---|
| CAS Number | 60796-65-8 | Molecular Weight | 236.221 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 422.7±45.0 °C at 760 mmHg | |
| Molecular Formula | C12H12O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 191.5±28.8 °C | |
Use of 5,7,8-Trimethoxycoumarin5,7,8-Trimethoxycoumarin is an anti-Parasite agent with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively[1]. |
| Name | 5,7,8-Trimethoxy-2H-chromen-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | 5,7,8-Trimethoxycoumarin is an anti-Parasite agent with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively[1]. |
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| Related Catalog | |
| In Vitro | 5,7,8-Trimethoxycoumarin (0-100 μM; 72 h) 抑制 Trypanosoma cruzi 和 L. amazonensis 的增殖[1]。 Cell Proliferation Assay[1] Cell Line: Trypanosoma cruzi (epimastigotes) and L. amazonensis (promastigote) Concentration: 1.5, 3.1, 6.2, 12.5, 25, 50 and 100 μM Incubation Time: 72 h Result: Inhibited the proliferation in a dose-dependent manner with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 422.7±45.0 °C at 760 mmHg |
| Molecular Formula | C12H12O5 |
| Molecular Weight | 236.221 |
| Flash Point | 191.5±28.8 °C |
| Exact Mass | 236.068466 |
| PSA | 57.90000 |
| LogP | 2.37 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.545 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2932209090 |
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~70%
5,7,8-Trimethox... CAS#:60796-65-8 |
| Literature: Riveiro, Maria E.; Maes, Dominick; Vazquez, Ramiro; Vermeulen, Monica; Mangelinckx, Sven; Jacobs, Jan; Debenedetti, Silvia; Shayo, Carina; De Kimpe, Norbert; Davio, Carlos Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6547 - 6559 |
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Detail
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| Literature: Kayser, Oliver; Kolodziej, Herbert Phytochemistry (Elsevier), 1995 , vol. 39, # 5 p. 1181 - 1186 |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 5,7,8-Trimethoxy-2H-chromen-2-one |
| Isoacronycidin |
| 2H-1-Benzopyran-2-one, 5,7,8-trimethoxy- |
| 5,7,8-Trimethoxycoumarin |
| 5,7,8-trimethoxy-chromen-2-one |
| isoacronycidine |