BioBioPha
China
Product Name: 5,7,8-Trimethoxycoumarin
Price: ￥2500.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5,7,8-TRIMETHOXYCOUMARIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

60796-65-8

60796-65-8 structure

60796-65-8 structure

Name: 5,7,8-Trimethoxycoumarin
Chemical Name: 5,7,8-Trimethoxy-2H-chromen-2-one
CAS Number: 60796-65-8
Molecular Formula: C₁₂H₁₂O₅
Molecular Weight: 236.221
Catalog: Natural product Coumarin
Create Date: 2017-06-21 05:01:19
Modify Date: 2024-01-06 11:01:25
5,7,8-Trimethoxycoumarin is an anti-Parasite agent with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively[1].

Name	5,7,8-Trimethoxy-2H-chromen-2-one
Synonyms	5,7,8-Trimethoxy-2H-chromen-2-one Isoacronycidin 2H-1-Benzopyran-2-one, 5,7,8-trimethoxy- 5,7,8-Trimethoxycoumarin 5,7,8-trimethoxy-chromen-2-one isoacronycidine

Description	5,7,8-Trimethoxycoumarin is an anti-Parasite agent with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively[1].
Related Catalog	Research Areas >> Infection
In Vitro	5,7,8-Trimethoxycoumarin (0-100 μM; 72 h) 抑制 Trypanosoma cruzi 和 L. amazonensis 的增殖[1]。 Cell Proliferation Assay[1] Cell Line: Trypanosoma cruzi (epimastigotes) and L. amazonensis (promastigote) Concentration: 1.5, 3.1, 6.2, 12.5, 25, 50 and 100 μM Incubation Time: 72 h Result: Inhibited the proliferation in a dose-dependent manner with IC50s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively.
References	[1]. Costa R S, et al. In vitro antileishmanial and antitrypanosomal activity of compounds isolated from the roots of Zanthoxylum tingoassuiba. Revista Brasileira de Farmacognosia, 2018, 28: 551-558.

Density	1.2±0.1 g/cm3
Boiling Point	422.7±45.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₂O₅
Molecular Weight	236.221
Flash Point	191.5±28.8 °C
Exact Mass	236.068466
PSA	57.90000
LogP	2.37
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.545

Hazard Codes	Xi
HS Code	2932209090

65162-31-4 structure

65162-31-4

21204-67-1 structure

21204-67-1

~70%

60796-65-8 structure

60796-65-8

Literature: Riveiro, Maria E.; Maes, Dominick; Vazquez, Ramiro; Vermeulen, Monica; Mangelinckx, Sven; Jacobs, Jan; Debenedetti, Silvia; Shayo, Carina; De Kimpe, Norbert; Davio, Carlos Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6547 - 6559

52249-80-6 structure

52249-80-6

127-09-3 structure

127-09-3

108-24-7 structure

108-24-7

77-78-1 structure

77-78-1

~%

Detail

Literature: Kayser, Oliver; Kolodziej, Herbert Phytochemistry (Elsevier), 1995 , vol. 39, # 5 p. 1181 - 1186

Precursor 5
65162-31-4 52249-80-6 127-09-3 108-24-7
77-78-1
DownStream 0

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%