5-Methoxy-3-indoleaceate

Modify Date: 2025-08-21 08:33:22

5-Methoxy-3-indoleaceate structure	Common Name	5-Methoxy-3-indoleaceate
	CAS Number	608-07-1	Molecular Weight	205.210
	Density	1.3±0.1 g/cm3	Boiling Point	445.9±30.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₁₄N₂O	Melting Point	245-250 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	223.5±24.6 °C
	Symbol	GHS07	Signal Word	Warning

Name	O-methylserotonin
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	445.9±30.0 °C at 760 mmHg
Melting Point	245-250 °C (dec.)(lit.)
Molecular Formula	C₁₁H₁₄N₂O
Molecular Weight	205.210
Flash Point	223.5±24.6 °C
Exact Mass	205.073898
PSA	51.04000
LogP	1.34
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.656
InChIKey	JTEJPPKMYBDEMY-UHFFFAOYSA-N
SMILES	COc1ccc2[nH]cc(CCN)c2c1
Storage condition	2-8°C

5-Methoxy-3-indoleaceate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL4059000

CHEMICAL NAME :: Indole, 3-(2-aminoethyl)-5-methoxy-

CAS REGISTRY NUMBER :: 608-07-1

BEILSTEIN REFERENCE NO. :: 0145587

LAST UPDATED :: 199709

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H14-N2-O

MOLECULAR WEIGHT :: 190.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 176 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 106 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - excitement Behavioral - muscle contraction or spasticity

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 8 mg/kg

SEX/DURATION :: male 20 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 11 mg/kg

SEX/DURATION :: female 12-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 240 mg/kg

SEX/DURATION :: female 1-2 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 3 gm/kg

REFERENCE :: EKSODD Eksperimental'naya Onkologiya. Experimental Oncology. (V/O Mezhdunarodnaya Kniga, 113095 Mosow, USSR) V.1- 1979- Volume(issue)/page/year: 7(4),26,1985

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NL4110000
HS Code	2933990090

Precursor 8
CAS#:61675-19-2 1H-Indole,5-met... CAS#:73-31-4 Melatonine CAS#:68935-49-9 5-methoxy-3-(2-... CAS#:1006-94-6 5-Methoxyindole
CAS#:67199-10-4 5-methoxy-Nb-(m... CAS#:102016-76-2 N-(2-(5-methoxy... CAS#:627086-10-6 2-(1-methanesul... CAS#:58635-45-3 methyl N-[2-(1H...
DownStream 10
CAS#:112081-40-0 N-[2-(5-methoxy... CAS#:111915-67-4 1-[2-(5-methoxy... CAS#:104510-12-5 N-[2-(5-methoxy... CAS#:50-67-9 5-Hydroxytryptamine
CAS#:3589-73-9 6-Methoxyharmalan CAS#:2009-03-2 N,O-dimethylser... CAS#:29745-42-4 N-[2-(5-methoxy... CAS#:96096-55-8 5-Methoxy-N-met...
CAS#:73-31-4 Melatonine CAS#:139564-01-5 N-[2-(5-methoxy...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.

Mol. Cell. Endocrinol. 404 , 1-8, (2015)

Melatonin and its metabolites including 6-hydroxymelatonin (6(OH)M), N(1)-acetyl-N(2)-formyl-5-methoxykynuramine (AFMK) and 5-methoxytryptamine (5MT) are endogenously produced in human epidermis. This...

The antioxidant behaviour of melatonin and structural analogues during lipid peroxidation depends not only on their functional groups but also on the assay system.

Biochem. Biophys. Res. Commun. 423(4) , 873-7, (2012)

There is no general agreement yet on the antioxidant effect of pineal indoles against lipid peroxidation. Accordingly, the main goal of the present work was to study the antioxidant activity of melato...

Hippocampal serotonin depletion is related to the presence of generalized tonic-clonic seizures, but not to psychiatric disorders in patients with temporal lobe epilepsy.

Epilepsy Res. 111 , 18-25, (2015)

Previous studies suggest that concentration of serotonin ([5-HT]) plays a pathogenic role in various types of epilepsy inhibiting seizures. However, most have not considered the clinical variables of ...

Name: Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryp...
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 1A
External Id: CHEMBL615963

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL4296184

Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186

Name: Binding affinity at rat 5-hydroxytryptamine 7 receptor.
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 7
External Id: CHEMBL620766

Name: Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA...
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL4296185

Name: Agonistic activity against rat 5-HT7 adenyl cyclase expressed in HEK293 cells; Active
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 7
External Id: CHEMBL619703

Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity

Total 248, Current Page 1 of 25

5-Methoxy-3-indoleacetic acid

Mexamine base

(5-Methoxy-1H-indol-3-yl)acetic acid

O-METHYLSEROTONIN

5MOT

5-Methoxyindoleacetic acid

EINECS 200-637-6

5-Methoxytryptamine

MFCD00005662

5-Methoxy-3-indoleacetate

5-Methoxy-3-indoleaceate

5-methoxy-1H-3-indoleacetic acid

5-Methoxyindole-3-acetic acid

Meksamin

Methoxyindoleacetic acid

O-methyl-5-HT

MEXAMINE

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-Methoxy-3-indoleaceate
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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BioBioPha
China
Product Name: 5-Methoxytryptamine
Price: ￥Inquiry/5mg
Purity: 98.0%
Delivery: 10 Day
Contact: Xueping-Zheng
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-Methoxytryptamine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5-Methoxy-3-indoleaceate
Price: ￥188.0/5g ￥658.0/25g
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

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5-Methoxy-3-indoleaceate

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles38

5-Methoxy-3-indoleaceateBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.