8-Chloroquinoline structure
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Common Name | 8-Chloroquinoline | ||
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CAS Number | 611-33-6 | Molecular Weight | 163.604 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 288.5±0.0 °C at 760 mmHg | |
Molecular Formula | C9H6ClN | Melting Point | -20 °C | |
MSDS | USA | Flash Point | 145.2±5.4 °C |
Name | 8-chloroquinoline |
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Synonym | More Synonyms |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 288.5±0.0 °C at 760 mmHg |
Melting Point | -20 °C |
Molecular Formula | C9H6ClN |
Molecular Weight | 163.604 |
Flash Point | 145.2±5.4 °C |
Exact Mass | 163.018875 |
PSA | 12.89000 |
LogP | 2.33 |
Vapour Pressure | 0.0±0.5 mmHg at 25°C |
Index of Refraction | 1.652 |
Water Solubility | SOLUBLE |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: Dust may cause mechanical irritation. Skin: No information regarding skin irritation and other potential effects was found. Ingestion: The toxicological properties of this substance have not been fully investigated. May cause central nervous system effects. Inhalation: Inhalation of dust may cause respiratory tract irritation. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 611-33-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: clear slight yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 288.5 deg C @ 760.00MM HG Freezing/Melting Point: -20 deg C Autoignition Temperature: Not available. Flash Point: > 110 deg C (> 230.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: soluble Specific Gravity/Density: Molecular Formula: C9H6ClN Molecular Weight: 163.61 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 611-33-6: VB2330000 LD50/LC50: Not available. Carcinogenicity: 8-Chloroquinoline - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 37/39 Wear suitable gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 611-33-6: No information available. Canada CAS# 611-33-6 is listed on Canada's NDSL List. CAS# 611-33-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 611-33-6 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
Hazard Codes | Xi:Irritant; |
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Risk Phrases | R36/37/38 |
Safety Phrases | S37/39-S26-S36/37/39 |
HS Code | 2933499090 |
~94% 8-Chloroquinoline CAS#:611-33-6 |
Literature: Wang, Chao; Flanigan, Darrin M.; Zakharov, Lev N.; Blakemore, Paul R. Organic Letters, 2011 , vol. 13, # 15 p. 4024 - 4027 |
~78% 8-Chloroquinoline CAS#:611-33-6 |
Literature: Rodriguez, J. Gonzalo; De Los Rios, Cristobal; Lafuente, Antonio Tetrahedron, 2005 , vol. 61, # 38 p. 9042 - 9051 |
~48% 8-Chloroquinoline CAS#:611-33-6 |
Literature: Tsuji, Yasushi; Huh, Keun-Tae; Watanabe, Yoshihisa Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1673 - 1680 |
~40% 8-Chloroquinoline CAS#:611-33-6 |
Literature: De Kimpe, Norbert; Keppens, Marian Tetrahedron, 1996 , vol. 52, # 10 p. 3705 - 3718 |
~% 8-Chloroquinoline CAS#:611-33-6 |
Literature: Tetrahedron, , vol. 52, # 10 p. 3705 - 3718 |
~% 8-Chloroquinoline CAS#:611-33-6 |
Literature: Tetrahedron, , vol. 52, # 10 p. 3705 - 3718 |
Precursor 7 | |
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DownStream 10 | |
HS Code | 2933499090 |
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Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Quinoline,8-chloro |
8-Chloroquinoline |
MFCD00047618 |
EINECS 210-265-6 |
8-chloro-quinoline |
Quinoline, 8-chloro- |
8-Chlor-chinolin |