8-Aminoquinoline

Modify Date: 2025-08-20 23:19:02

8-Aminoquinoline Structure
8-Aminoquinoline structure
Common Name 8-Aminoquinoline
CAS Number 578-66-5 Molecular Weight 144.17
Density 1.2±0.1 g/cm3 Boiling Point 289.8±0.0 °C at 760 mmHg
Molecular Formula C9H8N2 Melting Point 62-65ºC
MSDS Chinese USA Flash Point 171.5±8.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 8-Aminoquinoline


8-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 8-Aminoquinoline
Synonym More Synonyms

 8-Aminoquinoline Biological Activity

Description 8-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 289.8±0.0 °C at 760 mmHg
Melting Point 62-65ºC
Molecular Formula C9H8N2
Molecular Weight 144.17
Flash Point 171.5±8.1 °C
Exact Mass 144.068741
PSA 38.91000
LogP 1.88
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.708
Water Solubility slightly soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA9627000
CHEMICAL NAME :
Quinoline, 8-amino-
CAS REGISTRY NUMBER :
578-66-5
BEILSTEIN REFERENCE NO. :
0114474
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C9-H8-N2
MOLECULAR WEIGHT :
144.19
WISWESSER LINE NOTATION :
T66 BNJ JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
480 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Human Leukocyte
DOSE/DURATION :
100 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 39,285,1977

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R20/21/22;R36/37/38;R68
Safety Phrases S22-S26-S36/37/39
RIDADR NONH for all modes of transport
RTECS VA9627000
HS Code 29334990

 Synthetic Route

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles32

More Articles
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.

Malaria Journal 11 , 259, (2012)

The 8-aminoquinoline (8AQ) drug primaquine (PQ) is currently the only approved drug effective against the persistent liver stage of the hypnozoite forming strains Plasmodium vivax and Plasmodium ovale...

Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides.

Biol. Chem. 393(8) , 757-65, (2012)

In this study, we investigated the potential of four different aminoquinoline (AQ) compounds as fluorescent labels for glycan analysis using hydrophilic interaction liquid chromatography (HILIC) and f...

Copper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse model.

PLoS ONE 7(8) , e43105, (2012)

Alzheimer's disease (AD) is a neurodegenerative syndrom involving many different biological parameters, including the accumulation of copper metal ions in Aβ amyloid peptides due to a perturbation of ...

 Synonyms

8-Quinolinamine
MFCD00006809
quinolin-8-amine
EINECS 209-427-9
8-Aminoquinoline
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