1,1'-Diheptyl-4,4'-bipyridinium dibromide

Modify Date: 2024-01-02 16:26:40

1,1'-Diheptyl-4,4'-bipyridinium dibromide Structure
1,1'-Diheptyl-4,4'-bipyridinium dibromide structure
Common Name 1,1'-Diheptyl-4,4'-bipyridinium dibromide
CAS Number 6159-05-3 Molecular Weight 514.380
Density N/A Boiling Point N/A
Molecular Formula C24H38Br2N2 Melting Point 285 °C (dec.)(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of 1,1'-Diheptyl-4,4'-bipyridinium dibromide


DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.

 Names

Name 1-heptyl-4-(1-heptylpyridin-1-ium-4-yl)pyridin-1-ium,dibromide
Synonym More Synonyms

  Biological Activity

Description DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.
Related Catalog
In Vitro DHBP inhibits the calcium release induced by 2 mM caffeine and 2 μg/mL polylysine with an IC50 value of 5 μg/mL and 4 μg/mL, respectively. DHBP inhibits [3H]-ryanodine binding in a dose-dependent manner with an IC50 of 2.5 μg/mL and 90-100% inhibition at 20-30 μg/mL. Calcium uptake by SR is inhibited in the presence of caffeine and this inhibition is antagonized by concomitant addition of DHBP. Muscle twitches elicited by direct electrical muscle stimulation and contractions induced by either 10 mM caffeine or 1 fLM ryanodine are blocked by pretreatment with DHBP. DHBP blocks the calcium release from SR by direct interaction with the calcium release channel, also known as the ryanodine receptor[1].
References

[1]. Kang JJ, et al. Effects of bipyridylium compounds on calcium release from triadic vesicles isolated from rabbit skeletal muscle. Br J Pharmacol. 1994 Aug;112(4):1216-22.

 Chemical & Physical Properties

Melting Point 285 °C (dec.)(lit.)
Molecular Formula C24H38Br2N2
Molecular Weight 514.380
Exact Mass 512.140137
PSA 7.76000
Storage condition Store at RT

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

~%

1,1'-Diheptyl-4,4'-bipyridinium dibromide Structure

1,1'-Diheptyl-4...

CAS#:6159-05-3

Literature: Russian Journal of General Chemistry, , vol. 66, # 9 p. 1490 - 1496

~14%

1,1'-Diheptyl-4,4'-bipyridinium dibromide Structure

1,1'-Diheptyl-4...

CAS#:6159-05-3

Literature: Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 3 p. 367 - 372

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles3

More Articles
Electrochromic materials Mortimer, R. J.

Chem. Soc. Rev. 26(3) , 147-156, (1997)

Quasi-reversible electrochromic behavior of alkyl viologens dispersed mono-molecularly in double-stranded DNA chains Kakibe, T., & Ohno, H.

J. Mater. Chem. 19(28) , 4960-4964, (2009)

Ink-Jet Printing of Electron Donor/Acceptor Blends: Towards Bulk Heterojunction Solar Cells Marin, V., Holder, E., Wienk, M. M., Tekin, E., Kozodaev, D., & Schubert, U. S.

Macromol. Rapid Commun. 26(4) , 319-324, (2005)

 Synonyms

1,1'-Diheptyl-4,4'-bipyridinium dibromide
N,N'-diheptyl-4,4bipyridinium dibromide
N,N′-diheptyl-4,4′-bipyridinium dibromide
MFCD00011997
heptylviologen bromide
EINECS 228-178-7
heptyl viologen dibromide
4,4'-Bipyridinium, 1,1'-diheptyl-, bromide (1:2)
N,N'-diheptyl-4,4'-dipyridinium dibromide
4,4'-BIPYRIDINIUM, 1,1'-DIHEPTYL-, DIBROMIDE
DHBP dibromide
DHBP (dibromide)