trimecaine

Modify Date: 2025-08-22 18:35:03

trimecaine structure	Common Name	trimecaine
	CAS Number	616-68-2	Molecular Weight	248.364
	Density	1.0±0.1 g/cm3	Boiling Point	360.3±30.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₄N₂O	Melting Point	44°
	MSDS	N/A	Flash Point	171.7±24.6 °C

Name	2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
Synonym	More Synonyms

Density	1.0±0.1 g/cm3
Boiling Point	360.3±30.0 °C at 760 mmHg
Melting Point	44°
Molecular Formula	C₁₅H₂₄N₂O
Molecular Weight	248.364
Flash Point	171.7±24.6 °C
Exact Mass	248.188858
PSA	32.34000
LogP	2.82
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.544
InChIKey	GOZBHBFUQHMKQB-UHFFFAOYSA-N
SMILES	CCN(CC)CC(=O)Nc1c(C)cc(C)cc1C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AE2075000

CHEMICAL NAME :: Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-

CAS REGISTRY NUMBER :: 616-68-2

BEILSTEIN REFERENCE NO. :: 2697351

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H24-N2-O

MOLECULAR WEIGHT :: 248.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,222,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 295 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,402,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 187 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 50,112,1987

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 129 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,426,1976

2-nitromesitylene

CAS#:603-71-4

trimecaine

CAS#:616-68-2

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

2,4,6-Trimethyl...

CAS#:88-05-1

trimecaine

CAS#:616-68-2

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

2-Chloro-N-(2,4...

CAS#:3910-51-8

Diethylamine

CAS#:109-89-7

trimecaine

CAS#:616-68-2

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

Precursor 4
CAS#:603-71-4 2-nitromesitylene CAS#:88-05-1 2,4,6-Trimethyl... CAS#:3910-51-8 2-Chloro-N-(2,4... CAS#:109-89-7 Diethylamine
DownStream 10
CAS#:68638-18-6 diethyl-methyl-... CAS#:68638-19-7 N-ethyltrimecaine CAS#:68638-21-1 diethyl-[2-oxo-... CAS#:79143-64-9 N,N-Diethyl-N-(...
CAS#:79143-65-0 diethyl-[2-oxo-... CAS#:79143-66-1 benzyl-diethyl-... CAS#:79143-73-0 [2-(diethylamin... CAS#:79143-74-1 diethyl-bis[2-o...
CAS#:79143-75-2 diethyl-[2-(2-m... CAS#:79154-29-3 (2-chlorophenyl...

Name: S16 Schwann cell viability assay (CellTiter-Glo assay)
Source: NCGC
Target: N/A
External Id: cmt-p4-fda-celltiter_regid

Name: Biochemical firefly luciferase enzyme assay for NPC
Source: NCGC
Target: Luciferase [Photinus pyralis]
External Id: adst-fluc-km-fda-o1_regid

Name: S16 Schwann cell PMP22 intronic element firefly luciferase assay
Source: NCGC
Target: peripheral myelin protein 22 [Rattus norvegicus]
External Id: cmt-p4-fluc-fda_regid

Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100

Total 4, Current Page 1 of 1

Justecaina

Trimecain

Mesidicain

trimecaine

Mesokain

N,N-Diethyl-N-mesitylglycinamide

2-Diethylaminoacetyl-2',4',6'-trimethylanilide

Mesidicaine

N-sym-Trimethylphenyldiethylaminoacetamide

Diethylglycinemesidide

Mesocaine

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trimecaine

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

trimecaineBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.