trimecaine

Modify Date: 2026-07-14 18:57:19

trimecaine structure	Common Name	trimecaine
	CAS Number	616-68-2	Molecular Weight	248.364
	Density	1.0±0.1 g/cm3	Boiling Point	360.3±30.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₄N₂O	Melting Point	44°
	MSDS	N/A	Flash Point	171.7±24.6 °C

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.0±0.1 g/cm3
Boiling Point	360.3±30.0 °C at 760 mmHg
Melting Point	44°
Molecular Formula	C₁₅H₂₄N₂O
Molecular Weight	248.364
Flash Point	171.7±24.6 °C
Exact Mass	248.188858
PSA	32.34000
LogP	2.82
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.544
InChIKey	GOZBHBFUQHMKQB-UHFFFAOYSA-N
SMILES	CCN(CC)CC(=O)Nc1c(C)cc(C)cc1C

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AE2075000

CHEMICAL NAME :: Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-

CAS REGISTRY NUMBER :: 616-68-2

BEILSTEIN REFERENCE NO. :: 2697351

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H24-N2-O

MOLECULAR WEIGHT :: 248.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,222,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 295 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,402,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 187 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 50,112,1987

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 129 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,426,1976

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

2-nitromesitylene

CAS#:603-71-4

trimecaine

CAS#:616-68-2

Learn More

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

2,4,6-Trimethyl...

CAS#:88-05-1

trimecaine

CAS#:616-68-2

Learn More

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

2-Chloro-N-(2,4...

CAS#:3910-51-8

Diethylamine

CAS#:109-89-7

trimecaine

CAS#:616-68-2

Learn More

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 4
CAS#:603-71-4 2-nitromesitylene CAS#:88-05-1 2,4,6-Trimethyl... CAS#:3910-51-8 2-Chloro-N-(2,4... CAS#:109-89-7 Diethylamine
DownStream 10
CAS#:68638-18-6 diethyl-methyl-... CAS#:68638-19-7 N-ethyltrimecaine CAS#:68638-21-1 diethyl-[2-oxo-... CAS#:79143-64-9 N,N-Diethyl-N-(...
CAS#:79143-65-0 diethyl-[2-oxo-... CAS#:79143-66-1 benzyl-diethyl-... CAS#:79143-73-0 [2-(diethylamin... CAS#:79143-74-1 diethyl-bis[2-o...
CAS#:79143-75-2 diethyl-[2-(2-m... CAS#:79154-29-3 (2-chlorophenyl...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: S16 Schwann cell viability assay (CellTiter-Glo assay)
Source: NCGC
Target: N/A
External Id: cmt-p4-fda-celltiter_regid

Name: Biochemical firefly luciferase enzyme assay for NPC
Source: NCGC
Target: Luciferase [Photinus pyralis]
External Id: adst-fluc-km-fda-o1_regid

Name: S16 Schwann cell PMP22 intronic element firefly luciferase assay
Source: NCGC
Target: peripheral myelin protein 22 [Rattus norvegicus]
External Id: cmt-p4-fluc-fda_regid

Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100

Total 4, Current Page 1 of 1

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Justecaina

Trimecain

Mesidicain

trimecaine

Mesokain

N,N-Diethyl-N-mesitylglycinamide

2-Diethylaminoacetyl-2',4',6'-trimethylanilide

Mesidicaine

N-sym-Trimethylphenyldiethylaminoacetamide

Diethylglycinemesidide

Mesocaine

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What English synonyms does 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide have?

A: English synonyms of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide: Justecaina, Trimecain, Mesidicain, trimecaine, Mesokain, N,N-Diethyl-N-mesitylglycinamide, 2-Diethylaminoacetyl-2',4',6'-trimethylanilide, Mesidicaine, N-sym-Trimethylphenyldiethylaminoacetamide, Diethylglycinemesidide, Mesocaine.

Q: What are the downstream products of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: Related downstream products(CAS) of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide: 68638-18-6;68638-19-7;68638-21-1;79143-64-9;79143-65-0;79143-66-1;79143-73-0;79143-74-1;79143-75-2;79154-29-3.

Q: What is the LogP of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: LogP of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is 2.82.

Q: What is the polar surface area (PSA) of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: Polar surface area (PSA) of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is 32.34000.

Q: What is the melting point of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: Melting point of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is 44°.

Q: What is the SMILES notation of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: SMILES notation of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is CCN(CC)CC(=O)Nc1c(C)cc(C)cc1C.

Q: What is the molecular weight of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: Molecular weight of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is 248.364.

Q: What is the boiling point of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: Boiling point of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is 360.3±30.0 °C at 760 mmHg.

Q: What is the English name of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: The English name of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide.

Q: What is the CAS number of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide?

A: CAS number of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide is 616-68-2.

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.