chlordimeform

Modify Date: 2024-01-02 09:07:48

chlordimeform Structure
chlordimeform structure
Common Name chlordimeform
CAS Number 6164-98-3 Molecular Weight 196.67700
Density 1.1 Boiling Point 163~165
Molecular Formula C10H13ClN2 Melting Point 32ºC
MSDS Chinese USA Flash Point 130.839ºC
Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning

 Names

Name chlordimeform
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1
Boiling Point 163~165
Melting Point 32ºC
Molecular Formula C10H13ClN2
Molecular Weight 196.67700
Flash Point 130.839ºC
Exact Mass 196.07700
PSA 15.60000
LogP 2.86980
Index of Refraction 1.522

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ4375000
CHEMICAL NAME :
Formamidine, N'-(4-chloro-o-tolyl)-N,N-dimethyl-
CAS REGISTRY NUMBER :
6164-98-3
LAST UPDATED :
199707
DATA ITEMS CITED :
23
MOLECULAR FORMULA :
C10-H13-Cl-N2
MOLECULAR WEIGHT :
196.70
WISWESSER LINE NOTATION :
GR C1 DNU1N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
CIGET* Ciba-Geigy Toxicology Data/Indexes. (Ciba-Geigy Corp., 556 Morris Ave., Summit, NJ 07901) ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
263 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
225 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
71 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
625 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
>5800 mg/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 mg/kg/3D-I
TOXIC EFFECTS :
Behavioral - alteration of operant conditioning
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6552 mg/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1800 ug/kg
SEX/DURATION :
female 5-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - behavioral
TYPE OF TEST :
Specific locus test

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human HeLa cell
DOSE/DURATION :
1 mmol/L
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 11,184,1974 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,61,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 30,61,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning
Hazard Statements H302 + H312-H351-H410
Precautionary Statements P273-P280-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn,N
Risk Phrases 21/22-40-50/53
Safety Phrases 22-36/37-60-61
RIDADR 2761
RTECS LQ4375000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2925210000

 Synthetic Route

~89%

chlordimeform Structure

chlordimeform

CAS#:6164-98-3

Literature: Besan; Kulcsar; Kovacs Synthesis, 1980 , vol. NO.11, p. 883 - 884

~%

chlordimeform Structure

chlordimeform

CAS#:6164-98-3

Literature: Helvetica Chimica Acta, , vol. 56, p. 776 - 794

 Customs

HS Code 2925210000
Summary 2925210000 (e)-n'-(4-chloro-2-methylphenyl)-n,n-dimethylformimidamide。supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods)。VAT:17.0%。tax rebate rate:0.0%。MFN tarrif:6.5%。general tariff:30.0%

 Articles25

More Articles
Identification of the binding site for a low-molecular-weight inhibitor of plasminogen activator inhibitor type 1 by site-directed mutagenesis.

Biochemistry 37(5) , 1227-34, (1998)

A novel low-molecular-weight inhibitor, AR-H029953XX, was developed from a known fibrinolytic compound, flufenamic acid, which prevented complex formation of human plasminogen activator inhibitor type...

Interaction of formamidine pesticides with the presynaptic alpha(2)-adrenoceptor regulating.

Toxicol. Appl. Pharmacol. 172(3) , 179-85, (2001)

The effects of the formamidine pesticides amitraz and chlordimeform on the alpha(2)-adrenergic receptor subtype that mediates the release of [(3)H]noradrenaline by synaptosomes from rat hypothalami we...

Influence of the formamidine pesticide chlordimeform on ovulation in the female hamster: dissociable shifts in the luteinizing hormone surge and oocyte release.

Toxicol. Appl. Pharmacol. 121(2) , 279-90, (1993)

The formamidine pesticide chlordimeform (CDF) has been found to interfere with the hormonal control of ovulation in the rat by a presumptive disruption in the catecholaminergic regulation of the midcy...

 Synonyms

(Ξ)-N’-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide
Fundal
Methanimidamide
(EZ)-N2-(4-chloro-o-tolyl)-N1,N1-dimethylformamidine
CHLORDIMEFORM
Ovatoxion
chlorphenamidine
Ovatoxin
MFCD00055257
Bermat
Chlorfenamidine
Galecron
Chlorophenamidine
Acaron
N’-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide
N-(4-Chloro-2-methylphenyl)-N',N'-dimethylformamidine
N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide
EINECS 228-200-5
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