DeMethoxycapillarisin

Modify Date: 2025-08-25 13:32:18

DeMethoxycapillarisin Structure
DeMethoxycapillarisin structure
 Common Name DeMethoxycapillarisin
CAS Number 61854-36-2 Molecular Weight 286.236
Density 1.6±0.1 g/cm3 Boiling Point 535.9±50.0 °C at 760 mmHg
Molecular Formula C15H10O6 Melting Point N/A
MSDS N/A Flash Point 207.5±23.6 °C

 Use of DeMethoxycapillarisin


Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1].

 Names

Name 5,7-dihydroxy-2-(4-hydroxyphenoxy)chromen-4-one
Synonym More Synonyms

 DeMethoxycapillarisin Biological Activity

Description Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1].
Related Catalog
References

[1]. Govorko D, et al. Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1503-10.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 535.9±50.0 °C at 760 mmHg
Molecular Formula C15H10O6
Molecular Weight 286.236
Flash Point 207.5±23.6 °C
Exact Mass 286.047729
PSA 100.13000
LogP 2.70
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.729
InChIKey UBSCDKPKWHYZNX-UHFFFAOYSA-N
SMILES O=c1cc(Oc2ccc(O)cc2)oc2cc(O)cc(O)c12

 Safety Information

Hazard Codes Xi

 Synthetic Route

2,4-dimethoxy-6-(((4-methoxyphenoxy)carbonyl)oxy)benzoic acid structure

2,4-dimethoxy-6...

CAS#:78899-25-9

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475
benzyl 2,4-dimethoxy-6-(((4-methoxyphenoxy)carbonyl)oxy)benzoate structure

benzyl 2,4-dime...

CAS#:78899-17-9

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475
benzyl 5,7-dimethoxy-2-(4-methoxyphenoxy)-4-oxo-4H-chromene-3-carboxylate structure

benzyl 5,7-dime...

CAS#:78899-42-0

~%

DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475
benzyl 3-(2,4-dimethoxy-6-(((4-methoxyphenoxy)carbonyl)oxy)phenyl)-3-oxo-2-(triphenyl-l5-phosphanylidene)propanoate structure

benzyl 3-(2,4-d...

CAS#:78899-33-9

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475
5,7-dimethoxy-2-(4-methoxy-phenoxy)-chromen-4-one structure

5,7-dimethoxy-2...

CAS#:64964-85-8

~%

DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475
5,7-dimethoxy-2-(4-methoxyphenoxy)-4-oxo-4H-chromene-3-carboxylic acid structure

5,7-dimethoxy-2...

CAS#:78899-51-1

~%

DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475

 Synonyms

5,7-Dihydroxy-2-(4-hydroxyphenoxy)-4H-chromen-4-one
Demethoxycapillarisin
6-Demethoxycapillarisin
6-demethoxycapilarisin
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