Phosphate Salt of Tricyclic Nucleoside
Modify Date: 2025-08-25 10:24:43
Phosphate Salt of Tricyclic Nucleoside structure
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Common Name | Phosphate Salt of Tricyclic Nucleoside | ||
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| CAS Number | 61966-08-3 | Molecular Weight | 400.28 | |
| Density | 2.2±0.1 g/cm3 | Boiling Point | 832.8±75.0 °C at 760 mmHg | |
| Molecular Formula | C13H17N6O7P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 457.4±37.1 °C | |
Use of Phosphate Salt of Tricyclic NucleosideTriciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity[1]. |
| Name | triciribine phosphate |
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| Synonym | More Synonyms |
| Description | Triciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity[1]. |
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| Related Catalog | |
| References |
| Density | 2.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 832.8±75.0 °C at 760 mmHg |
| Molecular Formula | C13H17N6O7P |
| Molecular Weight | 400.28 |
| Flash Point | 457.4±37.1 °C |
| Exact Mass | 400.089630 |
| PSA | 200.81000 |
| LogP | -2.83 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.925 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| 5-Methyl-1-(5-O-phosphono-b-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
| 5-Methyl-1-(5-O-phosphono-β-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
| Pentaazaacenaphthylene-5' phosphate ester |
| 3-Amino-1,5-dihydro-5-methyl-1-b-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylene 5'-(Dihydrogen Phosphate) |
| Phosphate Salt of Tricyclic Nucleoside |
| Triciribine phosphate (USAN) |
| 1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-(5-O-phosphono-β-D-ribofuranosyl)- |
| VQD-002 |
| TCN-P |