Adrenalone hydrochloride

Modify Date: 2025-08-23 13:12:14

Adrenalone hydrochloride structure	Common Name	Adrenalone hydrochloride
	CAS Number	62-13-5	Molecular Weight	217.650
	Density	N/A	Boiling Point	405.6ºC at 760 mmHg
	Molecular Formula	C₉H₁₂ClNO₃	Melting Point	244-249 °C (dec.)
	MSDS	USA	Flash Point	N/A

Use of Adrenalone hydrochloride

Adrenalone hydrochloride is a selective α1-adrenoceptor agonist, used as a topical vasoconstrictor and hemostatic, used to prolong the action of local anesthetics.

Name	1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanone,hydrochloride
Synonym	More Synonyms

Description	Adrenalone hydrochloride is a selective α1-adrenoceptor agonist, used as a topical vasoconstrictor and hemostatic, used to prolong the action of local anesthetics.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Others

Boiling Point	405.6ºC at 760 mmHg
Melting Point	244-249 °C (dec.)
Molecular Formula	C₉H₁₂ClNO₃
Molecular Weight	217.650
Exact Mass	217.050568
PSA	69.56000
LogP	1.69280
InChIKey	CSRRBDMYOUQTCO-UHFFFAOYSA-N
SMILES	CNCC(=O)c1ccc(O)c(O)c1.Cl
Storage condition	2-8°C

Adrenalone hydrochloride MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM8225000

CHEMICAL NAME :: Acetophenone, 3',4'-dihydroxy-2-(methylamino)-, hydrochloride

CAS REGISTRY NUMBER :: 62-13-5

LAST UPDATED :: 199009

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H11-N-O3.Cl-H

MOLECULAR WEIGHT :: 217.67

WISWESSER LINE NOTATION :: QR BQ DV1M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 902 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 92,369,1948

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AM8225000
HS Code	2922509090

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

[Radiation protective effect of beta-ketoanalogs of hydroxyphenyl ethanolamines].

Radiats. Biol. Radioecol. 37(6) , 914-7, (1997)

Experiments are carried out on 3400 mice, irradiated in dose 8 Gy (LD97/30). beta-Ketoanalogs of adrenaline (adrenalone, 50-150 mumol/kg), m,p-dipivaloyladrenaline (20 mumol/kg) and phenylephrine (but...

Electron spin resonance-spin stabilization of semiquinones produced during oxidation of epinephrine and its analogues.

J. Biol. Chem. 259(1) , 354-8, (1984)

The ESR-spin stabilization approach has been employed to detect and characterize o-semiquinone radicals from the oxidation of epinephrine and related materials (norepinephrine, 3,4-dihydroxynorephedri...

Formation of adrenaline in the iris-ciliary body from adrenalone diesters.

Exp. Eye Res. 38(6) , 621-6, (1984)

Many diesters of adrenalone have high ocular sympathomimetic activity although adrenalone itself, even if delivered intraocularly, is practically inactive. Thus these diesters cannot be considered pro...

Name: Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay
Source: 24386
Target: N/A
External Id: Sarm1 Tir NADase inhibitors screen

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose

Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose

Name: Primary high throughput screening by co-culture imaging for identification hits as a ...
Source: 23209
Target: N/A
External Id: UIHTS20180925

Total 4, Current Page 1 of 1

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1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone hydrochloride (1:1)

Adrenalone hydrochloride

Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-, hydrochloride (1:1)

Adrenalone (hydrochloride)

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China
Product Name: Adrenalone hydrochloride
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Adrenalone hydrochloride

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