Dopamine hydrochloride
Dopamine hydrochloride structure
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Common Name | Dopamine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 62-31-7 | Molecular Weight | 189.639 | |
| Density | N/A | Boiling Point | 337.7ºC at 760 mmHg | |
| Molecular Formula | C8H12ClNO2 | Melting Point | 248-250 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 51.8 °F | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of Dopamine hydrochlorideDopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.Target: Dopamine ReceptorDopamine (or 3,4-dihydroxyphenethylamine) is a neuroendocrine transmitter in the catecholamine and phenethylamine families that plays a number of important roles in the brain and bodies of humans. Several important diseases of the nervous system are associated with dysfunctions of the dopamine system. Outside the nervous system, dopamine functions in several parts of the body as a local chemical messenger. In the blood vessels, it inhibits norepinephrine release and acts as a vasodilator; in the kidneys, it increases sodium excretion and urine output; in the pancreas, it reduces insulin production; in the digestive system, it reduces gastrointestinal motility and protects intestinal mucosa; and in the immune system, it reduces the activity of lymphocytes. A variety of important drugs work by altering the way the body makes or uses dopamine. Dopamine itself is available for intravenous injection: although it cannot reach the brain from the bloodstream, its peripheral effects make it useful in the treatment of heart failure or shock, especially in newborn babies. L-DOPA, the metabolic precursor of dopamine, does reach the brain and is the most widely used treatment for Parkinson's disease. From Wikipedia. |
Summary: Dopamine hydrochloride (3-hydroxytyramine hydrochloride) is a white crystalline compound with CAS number 62-31-7, molecular formula C8H12ClNO2, and molecular weight 189.639. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3-Hydroxytyramine hydrochloride |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.Target: Dopamine ReceptorDopamine (or 3,4-dihydroxyphenethylamine) is a neuroendocrine transmitter in the catecholamine and phenethylamine families that plays a number of important roles in the brain and bodies of humans. Several important diseases of the nervous system are associated with dysfunctions of the dopamine system. Outside the nervous system, dopamine functions in several parts of the body as a local chemical messenger. In the blood vessels, it inhibits norepinephrine release and acts as a vasodilator; in the kidneys, it increases sodium excretion and urine output; in the pancreas, it reduces insulin production; in the digestive system, it reduces gastrointestinal motility and protects intestinal mucosa; and in the immune system, it reduces the activity of lymphocytes. A variety of important drugs work by altering the way the body makes or uses dopamine. Dopamine itself is available for intravenous injection: although it cannot reach the brain from the bloodstream, its peripheral effects make it useful in the treatment of heart failure or shock, especially in newborn babies. L-DOPA, the metabolic precursor of dopamine, does reach the brain and is the most widely used treatment for Parkinson's disease. From Wikipedia. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Boiling Point | 337.7ºC at 760 mmHg |
|---|---|
| Melting Point | 248-250 °C(lit.) |
| Molecular Formula | C8H12ClNO2 |
| Molecular Weight | 189.639 |
| Exact Mass | 189.055649 |
| PSA | 66.48000 |
| LogP | 2.10130 |
| InChIKey | CTENFNNZBMHDDG-UHFFFAOYSA-N |
| SMILES | Cl.NCCc1ccc(O)c(O)c1 |
| Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
| Water Solubility | soluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H410 |
| Precautionary Statements | P273-P501 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 2 |
| RTECS | UX1092000 |
| HS Code | 29222900 |
| Flash Point(F) | 51.8 °F |
| Flash Point(C) | 11 °C |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
|
~96%
Dopamine hydroc... CAS#:62-31-7 |
| Literature: Kohno; Sasao; Murahashi Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 4 p. 1252 - 1254 |
|
~76%
Dopamine hydroc... CAS#:62-31-7 |
| Literature: Velcicky, Juraj; Soicke, Arne; Steiner, Roland; Schmalz, Hans-Guenther Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 6948 - 6951 |
|
~99%
Dopamine hydroc... CAS#:62-31-7 |
| Literature: Bernini, Roberta; Crisante, Fernanda; Barontini, Maurizio; Fabrizi, Giancarlo Synthesis, 2009 , # 22 art. no. P09409SS, p. 3838 - 3842 |
|
~%
Dopamine hydroc... CAS#:62-31-7 |
| Literature: Journal of the American Chemical Society, , vol. 133, # 18 p. 6948 - 6951 |
![tert-butyl N-[2-(3,4-dihydroxyphenyl)ethyl]carbamate structure](https://image.chemsrc.com/caspic/285/37034-31-4.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
|---|---|
| DownStream 10 | |
![N-[2-(3,4-dihydroxyphenyl)ethyl]octadeca-9,12,15-trienamide structure](https://image.chemsrc.com/caspic/238/105955-13-3.png)
CAS#:105955-13-3
CAS#:105955-12-2
CAS#:105955-10-0
CAS#:105955-11-1
CAS#:51-61-6![N-[2-(3,4-Dihydroxyphenyl)ethyl]-2-propenamide structure](https://image.chemsrc.com/caspic/086/201610-44-8.png)
CAS#:201610-44-8
CAS#:21581-49-7
CAS#:2494-12-4
CAS#:10597-60-1
CAS#:102-32-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 29222900 |
|---|
This table lists relevant public references with title, journal and publication metadata for this compound.
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'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile.
FEBS J. 282(6) , 1137-51, (2015) Norcoclaurine synthase (NCS) (EC 4.2.1.78) catalyzes the Pictet-Spengler condensation of dopamine and an aldehyde, forming a substituted (S)-tetrahydroisoquinoline, a pharmaceutically important moiety... |
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Permeation of Dopamine Sulfate through the Blood-Brain Barrier.
PLoS ONE 10 , e0133904, (2015) Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from per... |
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Increasing the Collision Rate of Particle Impact Electroanalysis with Magnetically Guided Pt-Decorated Iron Oxide Nanoparticles.
ACS Nano 9 , 7583-95, (2015) An integrated microfluidic/magnetophoretic methodology was developed for improving signal response time and detection limits for the chronoamperometric observation of discrete nanoparticle/electrode i... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3,4-Dihydroxy-b-phenethylamine Hydrochloride |
| 4-(2-aminoéthyl)benzène-1,2-diol chlorhydrate |
| b-(3,4-Dihydroxyphenyl)ethylamine Hydrochloride |
| Tensamin |
| 4-(2-Aminoethyl)benzene-1,2-diol hydrochloride (1:1) |
| Rascordin |
| Pyrocatechol, 4- (2-aminoethyl)-, hydrochloride |
| 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride (1:1) |
| 4-(2-aminoethyl)benzene-1,2-diol,hydrochloride |
| 1,2-Benzenediol, 4- (2-aminoethyl)-, hydrochloride |
| 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride (1:1) |
| 4-(2-aminoethyl)-Pyrocatechol hydrochloride |
| 4-(2-Aminoethyl)benzol-1,2-diolhydrochlorid |
| EINECS 200-527-8 |
| MFCD00012898 |
| 4-(2-Aminoethyl)catechol, hydrochloride |
| β-(3,4-Dihydroxyphenyl)ethylamine hydrochloride |
| Dopamine (hydrochloride) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of 3-Hydroxytyramine hydrochloride? |
| A: Melting point of 3-Hydroxytyramine hydrochloride is 248-250 °C(lit.). |
| Q: What is the polar surface area (PSA) of 3-Hydroxytyramine hydrochloride? |
| A: Polar surface area (PSA) of 3-Hydroxytyramine hydrochloride is 66.48000. |
| Q: What is the InChIKey of 3-Hydroxytyramine hydrochloride? |
| A: InChIKey of 3-Hydroxytyramine hydrochloride is CTENFNNZBMHDDG-UHFFFAOYSA-N. |
| Q: What is the boiling point of 3-Hydroxytyramine hydrochloride? |
| A: Boiling point of 3-Hydroxytyramine hydrochloride is 337.7ºC at 760 mmHg. |
| Q: What is the CAS number of 3-Hydroxytyramine hydrochloride? |
| A: CAS number of 3-Hydroxytyramine hydrochloride is 62-31-7. |
| Q: How is the water solubility of 3-Hydroxytyramine hydrochloride? |
| A: Water solubility of 3-Hydroxytyramine hydrochloride: soluble. |
| Q: What are the upstream materials of 3-Hydroxytyramine hydrochloride? |
| A: Related upstream materials(CAS) of 3-Hydroxytyramine hydrochloride: 1699-54-3;120-20-7;37034-31-4;93-17-4. |
| Q: What are the downstream products of 3-Hydroxytyramine hydrochloride? |
| A: Related downstream products(CAS) of 3-Hydroxytyramine hydrochloride: 105955-13-3;105955-12-2;105955-10-0;105955-11-1;51-61-6;201610-44-8;21581-49-7;2494-12-4;10597-60-1;102-32-9. |
| Q: What is the English name of 3-Hydroxytyramine hydrochloride? |
| A: The English name of 3-Hydroxytyramine hydrochloride is 3-Hydroxytyramine hydrochloride. |
| Q: What is the molecular formula of 3-Hydroxytyramine hydrochloride? |
| A: Molecular formula of 3-Hydroxytyramine hydrochloride is C8H12ClNO2. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |